Pulmonary Gas Exchange During Induction of Pulmonary Edema in Anesthetized Dogs

Said, Sami I.; Longacher, Joseph W.; Davis, Robert K.; Banerjee, Chandra M.; Davis, W. M.; Wooddell, W. Jeff

doi:10.1097/00132586-196512000-00006

Cited by 3 publications

(2 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It has already been noted that CT was somewhat reduced on these two ratios and it has been postulated that pulmonary congestion or oedema may have been developing in some of the animals at this time. Pulmonary oedema causes an increase in ventilation-perfusion inequality and in right-to-left shunt but it has been shown that compliance can be improved and shunting reduced by hyperinflations of the lung (Said et al, 1964). It is possible that the use of mechanical ventilation delayed the onset of pulmonary oedema in these animals.…”

Section: Total Venous Admixturementioning

confidence: 99%

The Effects of Variations in Inspiratory Expiratory Ratio on Cardiorespiratory Function During Controlled Ventilation in Normo-, Hypo- And Hypervolaemic Dogs

Flnlay¹,

WlGHTMAN²,

Adams³

et al. 1972

Survey of Anesthesiology

View full text Add to dashboard Cite

Changes in cardiorespiratory function resulting from the use of three different inspiratory: expiratory ratios (1:2, 0.5:2.5, and 2:1) have been studied in normo-, hypo-and hypervolaemic dogs. Deadspace/tidal volume ratio increased slightly with the 0.5:2.5 ratio in all the states of blood volume but the changes were not statistically significant. There was a significant increase in arterial-alveolar Pco 2 difference on the 0.5:2.5 ratio in the hypervolaemic state and there was a significant reduction in the Pco s difference with the 2:1 ratio in the normovolaemic state. There was a significant reduction in arterial Po, and a significant increase in venous admixture on the 0.5:2.5 ratio in the hypervolaemic state. Cardiac output was reduced after haemorrhage and increased after overtransfusion but there were no significant changes resulting from changes in the I: E ratio within each state of blood volume.

show abstract

Section: Total Venous Admixturementioning

confidence: 99%

The Effects of Variations in Inspiratory Expiratory Ratio on Cardiorespiratory Function During Controlled Ventilation in Normo-, Hypo- And Hypervolaemic Dogs

Flnlay¹,

WlGHTMAN²,

Adams³

et al. 1972

Survey of Anesthesiology

View full text Add to dashboard Cite

show abstract

“…The increase in A-aPo 2 after perfusion is a common finding. Its aetiology is unknown but it could be associated with multiple small emboli (Jones and Goodwin, 1965), pulmonary oedema (Stein et al, 1961;Said et al, 1964), or it could represent the earliest stages of the post-perfusion lung syndrome (Fordham, 1965;Hedley-Whyte et al, 1965;McClenahan, Young and Sykes, 1965). It is known that physiological deadspace is increased for periods of up to an hour after bypass (Pauca and Sykes, 1966) and it may be that the increased A-aPo 2 represents mainly a ventilation/perfusion abnormality due to cardiopulmonary bypass or drugs given after the procedure (Fordham and Resnekov, 1968).…”

Section: A-apomentioning

confidence: 99%

The Effect of Varying Inspiratory: Expiratory Ratios on Gas Exchange During Anaesthesia for Open-Heart Surgery

Sykes¹,

Lumley²

1969

British Journal of Anaesthesia

View full text Add to dashboard Cite

The risk factors and prognostic implication of acute pulmonary edema in resuscitated cardiac arrest patients

et al. 2015

View full text Add to dashboard Cite

ObjectivePulmonary edema is frequently observed after a successful resuscitation in out-of-hospital cardiac arrest (OHCA) patients. Currently, its risk factors and prognostic implications are mostly unknown.MethodsAdult OHCA patients with a presumed cardiac etiology who achieved sustained return of spontaneous circulation (ROSC) in emergency department were retrospectively analyzed. The patients were grouped according to the severity of consolidation on their initial chest X-ray (group I, no consolidation; group II, patchy consolidations; group III, consolidation involving an entire lobe; group IV, total white-out of any lung). The primary objective was to identify the risk factors of developing severe pulmonary edema (group III or IV). The secondary objective was to evaluate the association between long-term prognosis and the severity of pulmonary edema.ResultsOne hundred and seven patients were included. Total duration of cardiopulmonary resuscitation (CPR) and initial pCO2 level were both independent predictors of developing severe pulmonary edema with their odds ratio (OR) being 1.02 (95% confidence interval [CI], 1.00 to 1.04; per 1 minute) and 1.04 (95% CI, 1.01 to 1.07; per 1 mmHg), respectively. The long term prognosis was significantly poor in patients with severe pulmonary edema with a OR for good outcome (6-month cerebral performance category 1 or 2) being 0.22 (95% CI, 0.06 to 0.79) in group III and 0.16 (95% CI, 0.04 to 0.63) in group IV compared to group I.ConclusionThe duration of CPR and initial pCO2 level were both independent predictors for the development of severe pulmonary edema after resuscitation in emergency department. The severity of the pulmonary edema was significantly associated with long-term outcome.

show abstract

Pulmonary Gas Exchange During Induction of Pulmonary Edema in Anesthetized Dogs

Cited by 3 publications

References 0 publications

The Effects of Variations in Inspiratory Expiratory Ratio on Cardiorespiratory Function During Controlled Ventilation in Normo-, Hypo- And Hypervolaemic Dogs

The Effects of Variations in Inspiratory Expiratory Ratio on Cardiorespiratory Function During Controlled Ventilation in Normo-, Hypo- And Hypervolaemic Dogs

The Effect of Varying Inspiratory: Expiratory Ratios on Gas Exchange During Anaesthesia for Open-Heart Surgery

The risk factors and prognostic implication of acute pulmonary edema in resuscitated cardiac arrest patients

Contact Info

Product

Resources

About