2004
DOI: 10.2169/internalmedicine.43.227
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Pulmonary Langerhans' Cell Histiocytosis Presenting with an Endobronchial Lesion

Abstract: A 19-year-old man visited our hospital complaining of cough, sputum and low-grade fever. Chest radiograph and computed tomography findings suggested that he was suffering from pulmonary Langerhans' cell histiocytosis (PLCH). Bronchoscopy revealed a whitish elevated lesion at the bifurcation of the right upper lobe bronchus, and a specimen of this lesion showed the same pathological findings as pulmonary parenchymal lesions. Although there have been only a few reports of endobronchial LCH without pulmonary pare… Show more

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Cited by 4 publications
(3 citation statements)
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“…The endobronchial lesions improved three months after he stopped smoking, but the lung parenchymal lesions remained unchanged. This particular clinical course has been reported previously (10). Three months after the initial diagnosis, the patient stopped attending the hospital and resumed smoking (30 cigarettes/day) at 21 years of age.…”
Section: Introductionsupporting
confidence: 72%
“…The endobronchial lesions improved three months after he stopped smoking, but the lung parenchymal lesions remained unchanged. This particular clinical course has been reported previously (10). Three months after the initial diagnosis, the patient stopped attending the hospital and resumed smoking (30 cigarettes/day) at 21 years of age.…”
Section: Introductionsupporting
confidence: 72%
“…Des cas anecdotiques de forme trachéobronchiques d'HL pulmonaire ont été rapportés, mais sont un diagnostic d'exclusion [36].…”
Section: Histopathologie Pulmonaireunclassified
“…The pathogenesis and etiology of PLCH remain unknown, but it seems to be common among smokers (Friedman et al 1981), probably due to an inflammatory reaction of the lung tissue to the components of cigarette smoke (Suzuki et al 2004). Pulmonary Langerhans cell histiocytosis rarely occurs as a solitary nodule (Khoor et al 2001).…”
mentioning
confidence: 99%