Pulmonary Vascular Disease in Secundum Atrial Septal Defect with Pulmonary Hypertension

Clinical Use of Electrocardiography in Adults With Congenital Heart Disease

“…Right-axis deviation is common in adults with associated pulmonary vascular disease. 22 In contrast, left-axis deviation is rare but has been described in hereditary forms such as Holt-Oram syndrome and in older adults with presumably acquired left anterior fascicular block. Criteria for right atrial enlargement are fulfilled in 35% of patients.…”

Pulmonary vascular disease in shunted and nonshunted patients with tetralogy of fallot.

“…In cases of secundum atrial septal defect with thrombic PVD, the postoperative course is said to be good (Yamaki et al 1986(Yamaki et al , 1987. In our series of tetralogy of Fallot patients as well, the postoperative course following total correction was favorable, even in Cases 12, 14, 22 and 31 where severe thrombi were found.…”

Late Results after Repair of Complete Atrioventricular Canal.

“…Clapp et al (1990) documented a greater elevation of Rp in the first year of life and more rapid progression to fixed PVOD in Down patients than in non-Down patients. Because the pulmonary arterial wall responds to elevated pulmonary artery pressure by medial hypertrophy, the retarded development of medial hypertrophy in Down's syndrome is thought to be responsible for severe intimal lesions (Yamaki et al 1982). Late postoperative death due to PVOD has been reported (Studer et al 1982 ;Clapp et al 1990).…”