Pulse wave velocity is decreased in acromegaly compared to non-acromegaly study participants with similar cardiovascular risk profile

Filchenko, Irina; Korostovtseva, Lyudmila; Bochkarev, Mikhail; Boyarinova, M.; Alieva, A.; Rotar, O.; Sviryaev, Yurii; Tsoy, U. A.; Grineva, Elena

doi:10.1016/j.ghir.2021.101395

Cited by 2 publications

(1 citation statement)

References 28 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Arterial stiffness was increased in patients with acromegaly with cardiovascular risk factors, and that increased arterial stiffness was associated with hemodynamic (systolic and diastolic BPs) and metabolic (body mass index, fasting plasma glucose level, and HbA1C level) parameters [81]. PWV was decreased in acromegaly patients compared to non-acromegalic control participants with similar cardiovascular risk profiles [82]. In patients with active disease, preclinical markers of atherosclerosis were found to be worse compared to patients with inactive disease, but the role of diabetes and hypertension prevailed in hGH excess [78].…”

Section: In Acromegalymentioning

confidence: 92%

Myocardial, Valvular, and Vascular Structural and Functional Properties in Acromegaly

Nemes,

Kormányos,

Ambrus

et al. 2023

JCM

View full text Add to dashboard Cite

Acromegaly is an uncommon systematic endocrine disease caused by the hypersecretion of human growth hormone and, consequently, of insulin-like growth factor-1 during adulthood. Acromegaly could cause a typical cardiomyopathy characterized by left ventricular hypertrophy associated with diastolic dysfunction, which later could progress to systolic dysfunction. Moreover, some valvular and vascular abnormalities are also associated with acromegaly. This present review aims to summarize available information regarding acromegaly-associated abnormalities in myocardial, valvular, and vascular structural and functional properties and their relationship to disease activity and treatment options.

show abstract

Section: In Acromegalymentioning

confidence: 92%