Pulsed dye laser treatment of port-wine stains in pigmented skin

Intense pulsed light source for the treatment of dye laser resistant port‐wine stains

“…The final outcome has been found to be dependent on many factors, such as: (1) the applied light energy; (2) the pulse duration; (3) the wavelength or wavelength spectrum; (4) concomitant cooling of the skin surface 24,25 ; (5) anatomical location and size of the abnormal vessels; and (6) the degree of epidermal melanin concentration. [26][27][28] The lack of clearance of a subset of PDL-treated PWS prompts for investigations into new and improved treatment modalities. [7][8][9][10][11] In the present study, the IPL technology was used to treat PDL-resistant PWS with a response rate of 46.7% and with an average clearance for the responders of 83.9% (SD: 9.5%).…”

Evaluation of the treatment of port-wine stains with the 595-nm long pulsed dye laser: A large prospective study in adult Japanese patients

“…Finally, hypopigmentation was noted in 6% to 14% of our patients, and this is another adverse effect sometimes seen in darkskinned patients. 31,32 This adverse effect was nevertheless mild in our study, and it is reported to be a transient one when the cooling device is used. 15,16,25 To conclude, we performed a large prospective study of PWS treatment using 10-ms PDL at 595 nm with a dynamic cooling device in adult Japanese patients.…”

“…Patients with darker skin types are reported to be less responsive to laser treatments than lighter skin types and to require more treatment sessions because epidermal melanin present at higher concentrations can act as a competing target chromophore for laser light. 13,16,31,32 Third, the energy fluence was fixed at 12 J/cm 2 throughout the 4 treatment sessions in our protocol. This fluence was relatively low and did not cause purpura or caused only weak purpura in as much as 47% of patients, unlike the study by Bernstein and Brown 30 in which they determined the purpuragenic fluence for each patient by the test exposure.…”

Laser surgery: an approach to the pediatric patient

“…2,10,16 Although transient hyperpigmentation has been reported, especially in darker-skinned persons, permanent hyperpigmentation has not been described. 63 Permanent vascular blanching and atrophic scarring are very rare but potential complications, especially in younger patients. 64 It is important to inform parents of the potential risk and urge them to restrict their child's physical activity after laser treatment to avoid further scarring as a result of a traumatic event.…”