Pulsed dye laser versus intense pulsed light for facial erythema of rosacea: a systematic review and meta-analysis

Chang, Hua Ching; Chang, Yin Yi

doi:10.1080/09546634.2021.1959507

Cited by 8 publications

(4 citation statements)

References 10 publications

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“…The most used laser modality for vascular lesions is a pulsed dye laser (PDL) with a wavelength of 585-595 nm. Intense pulsed light (IPL) treatment consists of a broadband spectrum of light sources, ranging from 500 to 1,200 nm, that targets vascular lesions using filters of specific wavelength cutoffs [5]. Lower cutoffs are effective in treating telangiectasias in the superficial dermis, beneficial in reducing facial background erythema [6].…”

Section: Discussionmentioning

confidence: 99%

“…Lower cutoffs are effective in treating telangiectasias in the superficial dermis, beneficial in reducing facial background erythema [6]. Though both PDL and IPL displayed similar efficacy in reducing facial erythema [4,5,7], IPL provides some technical advantages, such as faster coverage and a lack of a consumable cooling technology (dye kit and cryogen spray cooling) [7]. Success in the treatment of erythema and telangiectasias using IPL has been widely documented [6]; Kassir et al [6] used IPL with 420-530 nm cutoff filter and about 70% of rosacea patients had reduction in redness and flushing; Papageorgiou et al [8] used IPL with 560 nm cutoff filter to successfully treat rosacea-related erythema and telangiectasia with minimal and selflimiting side effects.…”

Section: Discussionmentioning

confidence: 99%

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Menopausal facial erythema and flushing successfully treated with broadband light and botulinum toxin: a case report

Lee,

Cho

2023

Medical Lasers

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In menopausal patients, transient facial flushing may lead to persistent erythema and telangiectasias, causing psychological distress and a poor quality of life. Hormonal therapy is the primary treatment for menopausal symptoms, but its use remains limited due to the increased risk of cardiovascular and thromboembolic events. Nonhormonal therapies focus on lifestyle modifications, and energy-based devices have not been sufficiently evaluated. This case report describes the treatment given to a 52-year-old female presenting with menopausal facial erythema and flushing who received a combination of broadband light and intradermal botulinum toxin injections. This case highlights the need for further research that compares various energy-based modalities and their efficacy with established pharmacological treatments for menopausal flushing.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Menopausal facial erythema and flushing successfully treated with broadband light and botulinum toxin: a case report

Lee,

Cho

2023

Medical Lasers

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“…It was found that there was no significant difference between intense pulsed light and pulsed dye laser in terms of decreasing erythema. Finally, in a systematic review and meta-analysis on the use of intense pulsed light versus pulsed dye laser for treating facial erythema in rosacea, it was found that there were no significant differences between the two techniques regarding their effects in decreasing erythema [18].…”

Section: Discussionmentioning

confidence: 99%

Treatment of severe erythematotelangiectatic rosacea with intense pulsed light: a case report

Lee¹,

Lee²,

Chan³

2023

J Cosmet Med

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Erythematotelangiectatic rosacea is a common, long-standing inflammatory skin disorder of unclear origin. It is characterized by facial erythema involving mainly the central face (malar areas, chin, nasal area, and forehead region), with a range of clinical manifestations varying from blood vessels hyperactivity to sebaceous glands hyperplasia. These can have a considerable psychosocial impact on the patients. Intense pulsed light treatment can have significant effects on severe erythematotelangiectatic rosacea. We aimed to describe the treatment of severe erythematotelangiectatic rosacea with intense pulsed light. This article is a case report together with a literature review to explore the views of researchers on the treatment of erythematotelangiectatic rosacea with intense pulsed light. Pre-treatment and post-treatment clinical photographs are provided to show the effects of intense pulsed light therapy on severe erythematotelangiectatic rosacea. No comparisons were made with the other treatment modalities; nevertheless, this study provides an alternative treatment option for patients with severe erythematotelangiectatic rosacea. Our case report revealed that intense pulsed light using multiple filters at certain energy levels can effectively treat severe erythematotelangiectatic rosacea. We believe that, with more treatment sessions, patients can enjoy longer and more persistent results. Intense pulsed light is an effective treatment for erythematotelangiectatic rosacea. However, more erythematotelangiectatic rosacea cases treated with intense pulsed light will be required to consolidate intense pulsed light as one of the best treatment options for erythematotelangiectatic rosacea. Potential complications with intense pulsed light include post-inflammatory hyperpigmentation, burns, and pain.

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“…Compared with pulsed dye laser (PDL), IPL has milder adverse reactions, wide uses, high skin coverage, and low cost 9 . A meta‐study showed that PDL and IPL have similar efficacy in the treatment of facial erythema in patients with rosacea, but IPL has more technical advantages 10 . BBL is a module of the profile platform multifunctional laser treatment system produced by Sciton Company in the United States.…”

Section: Discussionmentioning

confidence: 99%

A randomized, controlled, split‐face study of botulinum toxin and broadband light for the treatment of erythematotelangiectatic rosacea

Tong

Luo

Gao

et al. 2022

Dermatologic Therapy

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To study the efficacy and safety of botulinum toxin (BTX) combined with broadband light (BBL) in the treatment of rosacea‐related erythema and flushing. A randomized, single‐blind, split‐face controlled study including 22 patients with erythemato telangiectatic rosacea were enrolled. Both cheeks were randomly divided into experimental group and control group. They were treated three times with an interval of 1 month. In the first treatment, the experimental group received BBL treatment and intradermal injection of BTX, and the control group received BBL treatment and intradermal injection of the same amount of normal saline; in the second and third treatments were both groups received the same BBL treatment. The patients were evaluated before the first treatment and 1, 2, 3, and 6 months after the treatment. Compared with the control group, the hydration in the experimental group increased and the global flushing symptom score (GFSS), VISIA red value, erythema index, transepidermal water loss, and sebum secretion decreased. The differences were statistically significant (p < 0.05). In the experimental group, at 3 months after the first treatment, compared with before treatment, the GFSS, VISIA red value, erythema index, transepidermal water loss and sebum secretion decreased the hydration increased. The sebum secretion returned to the pretreatment level in 6 months after treatment, and the other indexes maintained the level in 3 months after treatment. One patient had a slight lifting limitation of the corners of his mouth after 10 days of BTX injection, without special treatment, and recovered after 1 month. BTX intradermal injection combined with BBL has a definite therapeutic effect on the improvement of rosacea related erythema and flushing, which is better than simple BBL, and has high safety. It is worthy of clinical promotion.

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Pulsed dye laser versus intense pulsed light for facial erythema of rosacea: a systematic review and meta-analysis

Cited by 8 publications

References 10 publications

Menopausal facial erythema and flushing successfully treated with broadband light and botulinum toxin: a case report

Menopausal facial erythema and flushing successfully treated with broadband light and botulinum toxin: a case report

Treatment of severe erythematotelangiectatic rosacea with intense pulsed light: a case report

A randomized, controlled, split‐face study of botulinum toxin and broadband light for the treatment of erythematotelangiectatic rosacea

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