Pulsed electrochemical detection at gold electrodes applied to monoamines and diamines following their chromatographic separation

Biogenic amines and fish freshness assessment using a multisensor system based on voltammetric electrodes. Comparison between CPE and screen-printed electrodes

“…Electrochemical methods have also demonstrated to be useful to detect biogenic amines. The direct detection of various amines in water solutions by voltammetric methods using bare diamond [6,7] and metal electrodes [8,9] has been reported. Chemically modified electrodes (CME) containing surface-confined chemical functionalities exhibit some important advantages over conventional bare electrodes in terms of catalytic activity, selectivity and protection from fouling effects [10].…”

Electrooxidation of Aliphatic and Aromatic Amines at a Ni,Al Based Hydrotalcite Modified Electrode

“…Since elevated concentrations of polyamines or diamines in blood may be indicative of specific carcinomas, [2] these compounds have been proposed as tumor markers and utilized both for the screening and diagnosis of cancer [1]. Polyamine and diamine content could also represent an useful indicator of spoilage in foods, especially in seafood and other meats [2].…”

“…Polyamines and their acetylated derivatives are present in several biological systems and are involved in normal and neoplastic cell growth, in transcription and translation of RNA and in protein synthesis [1]. Since elevated concentrations of polyamines or diamines in blood may be indicative of specific carcinomas, [2] these compounds have been proposed as tumor markers and utilized both for the screening and diagnosis of cancer [1]. Polyamine and diamine content could also represent an useful indicator of spoilage in foods, especially in seafood and other meats [2].…”

Pulsed Amperometric Detection of Histamine at Glassy Carbon Electrodes Modified with Gold Nanoparticles

“…Concerning electrochemical detection, the amperometric responses from alkaline amine solutions at Cu [9] and Ni [10] metal electrodes involving the formation of surface oxides, have been used. Moreover, gold electrodes, at which the anodic signals from amine solutions are produced in a concomitant way to the appearance of surface AuO [11] have been also employed. In this case, the amine oxidation process gives rise to a rapid electrode surface fouling, and therefore pulsed electrochemical detection (PED) was applied.…”

“…However, a pH value of 13 is needed for the electrochemical detection step and so, a medium exchange of the eluate by post-column addition of concen-trated NaOH is required. Concerning the electrochemical detection mode, different potential-time waveforms have been employed, including pulsed amperometric detection [11,13,17], and integrated pulsed amperometric detection (IPAD) [1,16], which includes integrated square-wave detection (ISWD) [13 -15] and integrated voltammetric detection (IVD) [13]. PAD at Au electrodes has been widely used, although the performance of the technique for the detection of amines was not as good as that reported for other compounds [13], due to the consequence of the relatively high background current due to the formation of AuO on the electrode surface required for the anodic amines response.…”