Abstract:The Italian National Agency for New Technologies, Energy, and Sustainable Economic Development (ENEA) Neutron Active Interrogation (NAI) device is a tool designed to improve CBRNE defense. It is designed to uncover radioactive and nuclear threats including those in the form of Improvised Explosive Devices (IEDs), the so-called "dirty bombs". The NAI device, at its current development stage, allows to detect 6 g of 235 U hidden in a package. It is easily transportable, light in weight, and with a real-time response. Its working principle is based on two stages: (1) an "active" stage in which neutrons are emitted by a neutron generator to interact with the item under inspection, and (2) a "passive" stage in which secondary neutrons are detected originating a signal that, once processed, allows recognition of the offence. In particular, a clear indication of the potential threat is obtained by a dedicated software based on the Differential Die-Away Time Analysis method.