Purification, structure, lipid lowering and liver protecting effects of polysaccharide from Lachnum YM281

Qiu, Tao; Ma, Xiaojing; Ye, Ming; Yuan, Ruyue; Wu, Yanna

doi:10.1016/j.carbpol.2013.07.014

Cited by 74 publications

(44 citation statements)

References 26 publications

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“…The helical structure of polysaccharides was analysed by characterizing Congo red-polysaccharide reaction according to the method described by Qiu et al (2013). Different sets of solutions were prepared containing HWP, CAP and HAP (0.5 mg/ ml) in 0-0.5 M NaOH (increasing stepwise by 0.05 M increments) and 91 μM of Congo red.…”

Section: Congo Red Reactionmentioning

confidence: 99%

Influence of extraction parameters on physico-chemical characters and antioxidant activity of water soluble polysaccharides from Macrocybe gigantea (Massee) Pegler & Lodge

Khatua

Acharya

2015

J Food Sci Technol

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Polysaccharides from mushrooms are potentially active pharmaceutical ingredients and their action is dependent upon conformation, composition, size etc. In this context, three water soluble crude polysaccharide rich fractions viz. hot water extracted polysaccharide (HWP), cold alkaline extracted polysaccharide (CAP) and hot alkaline extracted polysaccharide (HAP) have been isolated using varying extraction parameters from Macrocybe gigantea, a well-known edible mushroom collected from Gangetic plain of West Bengal and authenticated by DNA barcoding of nrDNA ITS region. Physico-chemical investigation revealed that the fractions were mainly composed of β-configuration in pyranose form of sugars conjugated with small amount of protein. Further analysis presented that polysaccharides were composed of same monosaccharide even in similar order of ratio (D-glucose > D-galactose > D-mannose > D-xylose). However, Dglucose as well as β-glucan were found to be in the highest amount in CAP. The helical structure was determined by Congo red assay which indicated that polysaccharides were in aggregate forms except HWP which consisted of tertiary structure. These diverse structural features may have imparted effect on free radical scavenging activity of polysaccharides where HWP was the most active in all assays. HWP was proved to be a good scavenger of free radicals, strong chelator of ferrous ion and had high reducing power. Thus it can be inferred that HWP may foster further studies for searching active compound which might be used as ingredients of functional foods, nutraceuticals and pharmaceuticals. Moreover, to the best of our knowledge this is the first report on chemical composition and antioxidant activity of different crude polysaccharides from M. gigantea.

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Section: Congo Red Reactionmentioning

confidence: 99%

Influence of extraction parameters on physico-chemical characters and antioxidant activity of water soluble polysaccharides from Macrocybe gigantea (Massee) Pegler & Lodge

Khatua

Acharya

2015

J Food Sci Technol

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“…The ALP activity, ALT activity, AST activity, TC levels, TG levels, HDL-C levels, LDL-C levels and VLDL-C levels in serum were measured using an automatic biochemical analyzer (BS-380, Shenzhen, China). The atherogenic index (AI) was calculated as (TC-HDL-C)/HDL-C(Qiu, Ma, Ye, Yuan, & Wu, 2013).…”

mentioning

confidence: 99%

The antihyperlipidemic activities of enzymatic and acidic intracellular polysaccharides by Termitomyces albuminosus

Zhao

Zhang

et al. 2016

Carbohydrate Polymers

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“…Hyperlipidemia is a key factor in the development of some serious disorders, such as atherosclerosis, fatty liver disease, and cardio-cerebrovascular disease (Qiu et al 2013). Lowering of high serum and liver lipid level plays a significant role in prevention, arrest, and even reversion of atherosclerosis (Li et al 2010).…”

Section: Hypolipidemic Effectsmentioning

confidence: 99%

Polysaccharides from Medicinal Mushrooms and Their Antitumor Activities

Chen¹,

Li²

2015

Polysaccharides

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Purification, structure, lipid lowering and liver protecting effects of polysaccharide from Lachnum YM281

Cited by 74 publications

References 26 publications

Influence of extraction parameters on physico-chemical characters and antioxidant activity of water soluble polysaccharides from Macrocybe gigantea (Massee) Pegler & Lodge

Influence of extraction parameters on physico-chemical characters and antioxidant activity of water soluble polysaccharides from Macrocybe gigantea (Massee) Pegler & Lodge

The antihyperlipidemic activities of enzymatic and acidic intracellular polysaccharides by Termitomyces albuminosus

Polysaccharides from Medicinal Mushrooms and Their Antitumor Activities

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