Purpura rhumatoïde

Pillebout, Évangéline; Nochy, Dominique; Thervet, Éric

doi:10.1016/j.nephro.2009.02.001

Cited by 15 publications

(12 citation statements)

References 83 publications

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“…HSP is a multiorgan system disease and its major manifestations include cutaneous purpura, arthalgia, enteritis, and nephritis [41]. Clinical criteria for HSP according to EULAR include (1) purpura (mandatory criterion) or petechiae, with lower limb predominance, (not related to thrombocytopenia); (2) abdominal pain (may intussusception and gastrointestinal bleeding); (3) histological changes showing leucocytoclastic vasculitis with predominant IgA deposit or proliferative glomerulonephritis with predominant IgA deposit; (4) arthritis or arthralgias; (5) renal involvement with hematuria and/or proteinuria.…”

Section: Henoch Schönlein Purpuramentioning

confidence: 99%

Recent Understanding on Diagnosis and Management of Central Nervous System Vasculitis in Children

Iannetti

Zito

Bruschi

et al. 2012

Clinical and Developmental Immunology

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Central nervous system vasculitides in children may develop as a primary condition or secondary to an underlying systemic disease. Many vasculitides affect both adults and children, while some others occur almost exclusively in childhood. Patients usually present with systemic symptoms with single or multiorgan dysfunction. The involvement of central nervous system in childhood is not frequent and it occurs more often as a feature of subtypes like childhood polyarteritis nodosa, Kawasaki disease, Henoch Schönlein purpura, and Bechet disease. Primary angiitis of the central nervous system of childhood is a reversible cause of severe neurological impairment, including acute ischemic stroke, intractable seizures, and cognitive decline. The first line therapy of CNS vasculitides is mainly based on corticosteroids and immunosuppressor drugs. Other strategies include plasmapheresis, immunoglobulins, and biologic drugs. This paper discusses on current understanding of most frequent primary and secondary central nervous system vasculitides in children including a tailored-diagnostic approach and new evidence regarding treatment.

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Section: Henoch Schönlein Purpuramentioning

confidence: 99%

Recent Understanding on Diagnosis and Management of Central Nervous System Vasculitis in Children

Iannetti

Zito

Bruschi

et al. 2012

Clinical and Developmental Immunology

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“…HSP cannot be diagnosed by using an examination; reference must be made to clinical presentations and past history [ 3 , 4 ]. Every subject in our study was a child between the ages of 5 an 11 years old and had purpura of the lower extremities, AP and arthritis.…”

Section: Discussionmentioning

confidence: 99%

“…Henoch-Schonlein purpura (HSP), which is also called allergic purpura, anaphylactic purpura, is a kind of vasculitis and includes non-thrombocytopenic purpura, abdominal pain (AP), arthritis, and renal involvement [ 1 , 2 ]. Its etiology is not clear, but the immune complex within the walls of small vessel is assumed to be related to HSP [ 3 ]. A virus or bacterial infection, drugs, itches, and food may be associated with HSP, considering a preceding upper respiratory infection [ 1 - 3 ].…”

Section: Introductionmentioning

confidence: 99%

“…Its etiology is not clear, but the immune complex within the walls of small vessel is assumed to be related to HSP [ 3 ]. A virus or bacterial infection, drugs, itches, and food may be associated with HSP, considering a preceding upper respiratory infection [ 1 - 3 ]. HSP is common in children, especially children 4 to 6 years old, with a rate of 70.3 per 100,000 in children.…”

Section: Introductionmentioning

confidence: 99%

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Korean Herbal Medicine for Treating Henoch-Schonlein Purpura with Yin Deficiency: Five Case Reports

Kim

Ryu

Park

et al. 2014

Journal of Pharmacopuncture

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Objectives:The purpose of this study is to report the clinical effect of Korean medicine (KM) treatment for Henoch-Schonlein purpura (HSP).Methods:Five HSP patients who demonstrated a Yin deficiency and who had a history of a previous upper respiratory tract infection were included in this study. Four patients had arthritis and three had severe stomachache. One of them appeared to have proteinuria and hematuria before starting KM treatment.Results:All patients were improved with only herbal medicine, Jarotang (JRT). Purpura in the lower extremities and abdominal pain, which were not treated by using a corticosteroid, disappeared and had not recurred after 6 months.Conclusion:These cases indicate that JRT may be effective in treating HSP in patients who demonstrate Yin deficiency, even though the number of cases was limited to five.

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“…La vascularite à IgA (anciennement purpura rhumatoïde) est une vascularite systémique des petits vaisseaux en rapport avec des dépôts de complexes immuns contenant des immunoglobulines A [1]. Cette nouvelle nomenclature a été retenue lors de la conférence de consensus révisé de Chapel Hill en 2012 [2].…”

Section: Introductionunclassified

Pronostic rénal de la néphropathie des vascularites à IgA de l’adulte: étude monocentrique, à propos de 25 cas

et al. 2018

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La néphropathie de la vascularite à IgA conditionne le pronostic de cette affection chez l’adulte. Le but de notre étude était d’étudier les caractéristiques cliniques de cette atteinte rénale chez l’adulte et d’identifier les facteurs de pronostic rénal. Il s’agit d’une étude monocentrique rétrospective portant sur les patients ayant une vascularite à IgA (purpura rhumatoïde) (critères de l’EULAR) avec une atteinte rénale prouvée histologiquement et classée selon la classification de Pillebout. Nous avons analysé la survie rénale et identifier les facteurs de pronostic rénal. Vingt cinq patients ont été inclus (genre ratio M/F = 2,57) d’âge moyen au diagnostic du purpura rhumatoïde de 35,76 ans. Un purpura était présent dans 100% des cas avec une atteinte articulaire dans 28%. Une insuffisance rénale était présente dans 44% des cas. La classification histologique la plus fréquente était la classe II. Une rémission clinique a été observée dans 44% des cas et une évolution vers le stade terminal de l’insuffisance rénale chronique dans 36% des cas. La survie rénale à 195 mois était de 57%. Les facteurs pronostiques identifiés étaient l’atteinte digestive (p = 0,022), l’insuffisance rénale initiale (p = 0,0004), la classification glomérulaire (p = 0001) et la sévérité des lésions histologiques, le traitement par bloqueurs du système rénine angiotensine (p = 0,01) et les échanges plasmatiques (p = 0,03). Notre étude montre que l’atteinte rénale au cours des vascularites à IgA peut être relativement sévère avec un mauvais pronostic rénal. L’identification des facteurs pronostiques cliniques et histologiques pourrait guider l’élaboration d’études thérapeutiques prospectives.

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Purpura rhumatoïde

Cited by 15 publications

References 83 publications

Recent Understanding on Diagnosis and Management of Central Nervous System Vasculitis in Children

Recent Understanding on Diagnosis and Management of Central Nervous System Vasculitis in Children

Korean Herbal Medicine for Treating Henoch-Schonlein Purpura with Yin Deficiency: Five Case Reports

Pronostic rénal de la néphropathie des vascularites à IgA de l’adulte: étude monocentrique, à propos de 25 cas

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