Purtscher-like retinopathy preceding acute renal failure

Vicente, Jorge; Martino, M. Castilla; Díaz, Macarena; Rueda, T. Rueda; Socola, F.E. Molina; Morales, Alvárez; Herrero, F. López; Rodríguez, Alejandro; Rodríguez, López; Borrego, A. Martínez

doi:10.1016/j.oftale.2017.11.009

Cited by 3 publications

(3 citation statements)

References 7 publications

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“…We describe two unique cases wherein our patients experienced sudden bilateral vision loss after incidentally being diagnosed with COVID-19. Commonly reported causes of Purtscher-like retinopathy include acute pancreatitis, 14 , 15 renal failure, 16 , 17 , 18 dermatomyositis, 19 , 20 , 21 and disseminated intravascular coagulation (DIC). 13 , 22 In order to make a diagnosis of Purtscher-like retinopathy, the patient must have three of the following five criteria: Purtscher flecken, retinal hemorrhages, cotton-wool spots, probably explanatory etiology, and complementary investigation compatible with diagnosis.…”

Section: Discussionmentioning

confidence: 99%

Purtscher-like retinopathy in patients with COVID-19

Kalavar,

El Khatib,

Suelves

et al. 2023

American Journal of Ophthalmology Case Reports

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Section: Discussionmentioning

confidence: 99%

Purtscher-like retinopathy in patients with COVID-19

Kalavar,

El Khatib,

Suelves

et al. 2023

American Journal of Ophthalmology Case Reports

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“…Purtscher-like retinopathy (PLR) is an uncommon occlusive microangiopathy associated with various systemic conditions. The most common causes are acute pancreatitis, renal failure, and autoimmune diseases, including systemic lupus erythematosus (SLE) and dermatomyositis [ 1 , 2 , 3 , 4 ]. The pathogenesis remains unclear, and several mechanisms have been proposed to explain the characteristic fundus findings.…”

Section: Introductionmentioning

confidence: 99%

Purtscher-like Retinopathy in a Patient with Systemic Sclerosis: A Case Report and Narrative Review

Pieklarz

Gińdzieńska-Sieśkiewicz

Zawadzka

et al. 2023

Biomedicines

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Purtscher-like retinopathy (PLR) is an uncommon occlusive microangiopathy associated with various systemic conditions. We report a case of PLR related to severe progressive systemic sclerosis (SSc), an autoimmune disease characterized by widespread angiopathy and fibrosis, in a 44-year-old Caucasian male diagnosed with early diffuse cutaneous systemic sclerosis (dSSc). Upon ophthalmological examination, pathognomonic fundoscopy abnormalities were found. Spectral domain optical coherence tomography (SD-OCT), angio-OCT, and visual field results are documented at initial diagnosis and follow-up visits. The detailed ophthalmological assessment is juxtaposed with rheumatological evaluation and treatment. Current literature on probable pathophysiological mechanisms is reviewed in accordance with the described case. The PLR seems to be connected to severe SSc-related angiopathy initiated by capillary endothelial damage, with ultimate arteriolar precapillary occlusion in the inner retinal layer. Although this is not routinely recommended, we suggest that ophthalmological examinations may be advantageous in patients with SSc, as serious eye pathology may be present despite the lack of symptoms reported by the patient. Patients with PLR require a differential diagnosis and regular follow-up. Proper treatment of the underlying disease may have beneficial effects on the natural course of PLR.

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“…Purtscher's-like retinopathy is associated with non-traumatic causes [5]. Its occurrence has been reported in many disorders such as antibiotic anaphylaxis, myocardial infarction, connective tissue diseases, renal failure, childbirth, and bone marrow transplant [5][6][7][8]. Furthermore, Purtscher's-like retinopathy is rare with an incidence rate of less than 0.24 cases per million, and it is also a complication of AP [5].…”

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confidence: 99%