Pyoderma gangrenosum complicated by ecthyma gangrenosum

Yang, C-C.; Hsieh, F-S.; Lee, J.Y-Y.

doi:10.1111/j.1365-2133.2004.05922.x

Cited by 9 publications

(6 citation statements)

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“…Exclusion of infection through histologically indicated stains and tissue cultures aids in diagnosis but is not required because superinfection is possible. 22,46 Therefore, exclusion of infection is best done through histology. Although superficial wound cultures could be obtained on a case-by-case basis, it is not part of our diagnostic criteria because it may overestimate bacterial colonization and superinfection while underestimating slow-growing bacteria, fungus (eg, Sporothrix schenckii), mycobacteria, and viruses.…”

Section: Discussionmentioning

confidence: 99%

“…Case reports of ulcerative PG and mimickers were collected through a PubMed search for cases published in respected peer-reviewed medical journals chosen by impact factor ( Journal of the American Academy of Dermatology , JAMA Dermatology , British Journal of Dermatology , Journal of the European Academy of Dermatology and Venereology , and Acta Dermato-Venereologica ) from 2001 to 2016 . To balance the number of PG cases and mimics, additional cases of non-PG ulcers were found using the search terms ulcer and vasculitis , ulcer and venous , and ulcer and calciphylaxis because such ulcers are often misdiagnosed as PG (eAppendix 2 in the Supplement).…”

Section: Methodsmentioning

confidence: 99%

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Diagnostic Criteria of Ulcerative Pyoderma Gangrenosum

et al. 2018

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Diagnostic Criteria of Ulcerative Pyoderma Gangrenosum

et al. 2018

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“…Bacteraemia in EG results in an occlusive vasculitis, causing local infarction . The skin lesions of EG evolve rapidly through a characteristic pattern of oedema, erythema, haemorrhagic bullae and frank necrosis .…”

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confidence: 99%

Ecthyma gangrenosum, an important cutaneous infection to recognize in the immunosuppressed patient

2017

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The literature on the treatment of MC with HP is limited to an open study on 12 immunocompetent children who were treated with HP 1% cream applied twice daily for 21 days. In eight patients (67%), complete remission of MC lesions was observed, and in the remaining four patients, a reduction of 70% in the number of the lesions was recorded. No recurrence was observed over an average follow-up period of 6 months.5 Furthermore, an 8-month-old girl with multiple MC lesions on the genital area was successfully treated with the same cream under occlusion.2 To our knowledge, no controlled clinical studies have been published.Our study, based on a rather small number of patients, but on a high number of lesions, shows that HP 1.8% gel, applied twice daily under occlusion for 3 weeks, is a potential treatment of immunocompetent children with multiple MC. However, a higher number of patients and lesions is necessary for definitive conclusions.

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“…Infections, including cellulitis, herpetic ulcers, Buruli ulcers, atypical mycobacterial infections, cutaneous tuberculosis, ecthyma [28], leishmaniasis and other deep fungal infections (e.g., sporotrichosis) [29,30], can also mimic PG. In addition to vascular inflammation, occlusion of the vessels must also be considered in the differential diagnosis of PG.…”

Section: Differential Diagnosismentioning

confidence: 98%

Pyoderma gangrenosum: an expert commentary

Jackson¹,

Callen²

2006

Expert Review of Dermatology

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Pyoderma gangrenosum is an inflammatory condition that is characterized by ulcerations of the skin, but may involve other organs. Classically, pyoderma gangrenosum starts as a small pustule that progresses to the classic ulceration with an overhanging violaceous border. Pathergy, the development of cutaneous involvement at sites of trauma, is common. Pyoderma gangrenosum occurs in association with other diseases in approximately 50% of patients and is most commonly associated with inflammatory bowel disease, myeloproliferative disorders and various arthritides. The diagnosis of pyoderma gangrenosum is made by excluding other conditions, such as malignancy, infection, vasculitis and trauma. Treatment of pyoderma gangrenosum involves treatment of an associated disease if present, and topical and/or systemic corticosteroids and/or immunosuppressive therapies.

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Pyoderma gangrenosum complicated by ecthyma gangrenosum

Cited by 9 publications

References 0 publications

Diagnostic Criteria of Ulcerative Pyoderma Gangrenosum

Diagnostic Criteria of Ulcerative Pyoderma Gangrenosum

Ecthyma gangrenosum, an important cutaneous infection to recognize in the immunosuppressed patient

Pyoderma gangrenosum: an expert commentary

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