Pyogenic abscess of the liver

Ochsner, Alton; DeBakey, Michael E.; Murray, Samuel

doi:10.1016/s0002-9610(38)90618-x

Cited by 316 publications

(73 citation statements)

References 51 publications

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“…Similar results have been reported by Mishra et al and Singh and Srivastava studies. 3 Males (93.3%) were predominantly affected with amoebic liver abscess in the present study, which were similar to other studies like Debakey and Oschner, Raghavan et al, Habibullah et al and Katzenstein et al 4,5,6,7 Out of 45 cases, there were 42 male patients (93.3%) and 3 female patients (6.6%). The male-to-female ratio is 14:1.…”

Section: Discussionsupporting

confidence: 91%

Clinical Presentation and Management of Amoebic Liver Abscess

Naveen¹,

R²,

M³

et al. 2015

jemds

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BACKGROUND AND OBJECTIVESALA has gained importance during recent years as a result of increasing world travel, economic globalization and the growing number of chronically immunosuppressed people. AIDS and the increasing use of organ transplants have led to a new population at risk. In our study we aimed to analyse the clinical presentation and management of Amoebic liver abscess at Sree Rajarajeshwari Medical College and Hospital, Bangalore.

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Section: Discussionsupporting

confidence: 91%

Clinical Presentation and Management of Amoebic Liver Abscess

Naveen¹,

R²,

M³

et al. 2015

jemds

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“…In 1938, the largest series of pyogenic and amoebic liver abscesses in the literature for the time was published [1], and despite a refinement in diagnostic and therapeutic modalities since then, liver abscess remains a serious condition with a high morbidity and mortality rate [1]- [3].…”

Section: Introductionmentioning

confidence: 99%

Clinical and Pathological Comparison of Pyogenic and Amoebic Liver Abscesses

Bhatti¹,

Ali²,

Satti³

et al. 2014

AID

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BACKGROUND: Pyogenic and amoebic liver abscesses are rare, potentially lethal conditions. In this study, we aimed to examine the clinical and pathological differences between them. METHODS: Patients with confirmed liver abscesses were divided into two groups: the pyogenic (n = 47) and amoebic group (n = 21), which were analyzed for differences in clinical and laboratory findings. RESULTS: Amoebic liver abscesses presented most frequently in young adults (14 -30 years; 71%), whereas pyogenic liver abscesses were most commonly observed in adults 41 -50 years (49%). Indirect hemagglutination test revealed a 100% positive response in the amoebic group, whereas 68% of the pyogenic group presented with blood/pus culture. Multiple abscesses were observed in 66% and 24% of patients in the pyogenic and amoebic group, respectively. CONCLUSIONS: Pyogenic abscesses were commonly observed in older patients, and were associated with features such as markedly deranged liver function test, higher prothrombin time, and multiple abscesses, compared to amoebic abscess. Early and improved diagnoses and differentiation between the two conditions, followed by the correct treatment, can help prevent serious complications and lead to an overall improved mortality rate.

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“…Ochsner et al [1] reported the first comprehensive study of pyogenic liver abscesses (PLAs) in 1938, which were predominantly diagnosed in young men, were associated with pyelophlebitis and accompanied by a high fatality rate (77%).…”

Section: Introductionmentioning

confidence: 99%

Pyogenic liver abscess in the elderly: clinical features, outcomes and prognostic factors

et al. 2008

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Background: pyogenic liver abscess (PLA) is a potentially life-threatening disease in middle-to-old aged persons. Objective: to compare the differences in clinical features and outcomes between older and younger PLA patients, and to identify predictors of outcomes in older patients. Design: retrospective chart review of all PLA patients between July 1999 and June 2007. Setting: a 1,600-bed primary and tertiary care centre. Subjects: in total, 339 patients were enrolled and included 118 ≥65 years of age (the elderly group) and 221 patients <65 years of age (the non-elderly group). Methods: clinical features, laboratory, imaging and microbiologic findings, treatment and outcomes for each of the included patients were collected. The predictor of outcome was determined using logistic regression and purposeful selection of covariates. Results: the elderly group had a higher APACHE II score on admission, a biliary abnormality, a malignancy, a pleural effusion, polymicrobial, anaerobic or multi-drug-resistant isolates, inappropriate initial antibiotics, a longer hospitalisation and a longer parenteral antibiotic treatment period than the non-elderly group, whereas the non-elderly group was more likely to be alcoholic men with cryptogenic origin of abscess and Klebsiella pneumoniae infection. There was no difference in case fatality between the elderly (13.6%) and non-elderly (8.6%) groups despite the elderly group having a poorer host status on admission. In multivariate analysis, age (P = 0.028) and APACHE II score at admission ≥15 (P = 0.001) were risk factors, but K. pneumoniae infection (P = 0.012) was a protective factor for fatality in older PLA patients. Conclusions: these data suggest that older PLA patients wound have a fair outcome compared to younger patients, but require longer hospitalisations.

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Pyogenic abscess of the liver

Cited by 316 publications

References 51 publications

Clinical Presentation and Management of Amoebic Liver Abscess

Clinical Presentation and Management of Amoebic Liver Abscess

Clinical and Pathological Comparison of Pyogenic and Amoebic Liver Abscesses

Pyogenic liver abscess in the elderly: clinical features, outcomes and prognostic factors

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