Pyogenic brain abscess, a 15 year survey

Helweg‐Larsen, Jannik; Astradsson, Arnar; Richhall, Humeira; Erdal, Jesper; Laursen, Alex Lund; Brennum, Jannick

doi:10.1186/1471-2334-12-332

Cited by 175 publications

(185 citation statements)

References 32 publications

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“…58,59 Most patients present in the third or fourth decade of life, and brain abscess is more commonly diagnosed in men. 57,59 Mortality from brain abscess has historically run as high as 40%, but has decreased to 10% since 2000, owing much to advances in diagnostic imaging and management strategies. 57 …”

Section: Brain Abscessmentioning

confidence: 99%

Diagnosis and Treatment of Central Nervous System Infections in the Emergency Department

Dorsett

Liang

2016

Emergency Medicine Clinics of North America

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Central nervous system (CNS) infections, including meningitis, encephalitis, and brain abscess, are rare but time-sensitive emergency department (ED) diagnoses. Patients with CNS infection can present to the ED with a host of non-specific signs and symptoms, including headache, fever, altered mental status, and behavioral changes. In meningitis, the classic triad of fever, neck stiffness, and altered mental status occurs in only a minority of patients. Classic physical examination maneuvers, such Kernig’s and Brudzinski’s signs, are relatively insensitive although specific for predicting cerebrospinal fluid (CSF) pleocytosis. Patients with parenchymal involvement, as occurs with encephalitis and brain abscess, may also have focal neurologic deficits or seizures. Neuroimaging and CSF fluid analysis can appear benign early in the course of meningitis and encephalitis, and clinicians should not be falsely reassured. Delaying antibiotic and antiviral therapies negatively impacts outcomes, particularly with bacterial meningitis and herpes simplex virus encephalitis. As with other rare, life-threatening diagnoses encountered in emergency medicine, the diagnosis and treatment of CNS infections requires vigilance and a high index of suspicion based on the history and physical examination which must be confirmed with appropriate imaging and laboratory evaluation.

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Section: Brain Abscessmentioning

confidence: 99%

Diagnosis and Treatment of Central Nervous System Infections in the Emergency Department

Dorsett

Liang

2016

Emergency Medicine Clinics of North America

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“…Any treatment, conservative or surgical, for IV brain abscess may not be able to give complete cure 4,8 and ultimate prognosis is poor. Though conservative management can be initially started, ultimately surgical drainage and evacuation followed by ventriculo-peritoneal shunting is the defi nite mode of treatment.…”

Section: Discussionmentioning

confidence: 99%

A Case of Primary Intraventricular Brain Abscess in a Child: A Challenge to Conquer

Bajracharya¹,

Shrestha²,

Singh³

et al. 2016

Nep J Neurosci

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Primary intraventricular brain abscess is a rare entity. Not many cases are reported yet. Moreover, proper guidelines for the treatment, conservative treatment or surgery, has not yet been established. Its outcome is also unpredictable and usually poor.We present a 11-year-old girl with wide spread intraventricular brain abscess. There was no obvious cause for the abscess formation. Cardiac status was normal by history and ECHO. She was treated surgically with external ventricular drainage (EVD). There was significant improvement after EVD. Intraventricular flushing was done with the solution of injection Gentamycin and hydrocortisone. However, the patient expired while planned for discharge from the hospital due to sudden cardiac arrest.A bigger study is needed to assess the various factors of intraventricular brain abscess including epidemiology, treatment, outcome etc in the Nepalese context.Nepal Journal of Neuroscience 12:88-90, 2015

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“…The symptoms are no't specific. The patients appear with headache, fever, nausea, seizures and neurological deficits [5]. For the diagnosis of subdural empyema, contrast-enhanced CT scan or better MRI are gold-standard diagnostic methods [6].…”

Section: Introductionmentioning

confidence: 99%

Pediatric parafalcine empyemas

Niklewski

Petridis

Hourani

et al. 2013

Journal of Surgical Case Reports

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Subdural intracranial empyemas and brain abscesses are a rare complication of bacterial sinusitis. Pediatric parafalcine abscesses are a rare entity with different treatment compared with other brain abscesses. We present two pediatric cases with falcine abscess as a sinusitis complication and introduce our department’s treatment management. In addition a review of literature is performed. Surgical cases of our department and their management are compared with the current literature. In our cases, both of the children showed a recurrent empyema after the first surgical treatment and antibiotic therapy. A second surgical evacuation was necessary. The antibiotic therapy was given for 3 months. Short-time follow-up imaging is necessary irrespective of infection parameters in blood and patient's clinical condition. Especially in parafalcine abscesses a second look may be an option and surgical treatment with evacuation of pus is the treatment of choice if abscess remnants are visualized.

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Pyogenic brain abscess, a 15 year survey

Cited by 175 publications

References 32 publications

Diagnosis and Treatment of Central Nervous System Infections in the Emergency Department

Diagnosis and Treatment of Central Nervous System Infections in the Emergency Department

A Case of Primary Intraventricular Brain Abscess in a Child: A Challenge to Conquer

Pediatric parafalcine empyemas

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