Pyogenic granuloma associated with Actinomyces israelii

Kuyama, Kayo; Fukui, Kenji; Ochiai, Eriko; Wakami, Masanobu; Oomine, Hirotaka; Sun, Yan; Morikawa, Miyuki; Iwadate, Kimiharu; Yamamoto, Hirotsugu

doi:10.1016/j.jds.2012.09.026

Cited by 4 publications

(3 citation statements)

References 15 publications

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“… 6 In oral soft tissues, lesions associated with Actinomyces of the gingiva, the tongue, the buccal, and the tonsil have been reported. 7 , 8 , 9 In this study, four of the cases (44.4%) were suspected to have tumors at initial diagnosis. Additionally, various antibiotics were used based on different initial diagnoses.…”

Section: Discussionmentioning

confidence: 71%

Orofacial soft tissues actinomycosis: A retrospective, 10-year single-institution experience

Matsuda

Yoshida

Yoshimura

2021

Journal of Dental Sciences

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Background/purpose Actinomycosis is a rare disease. It can often mimic other infectious or malignant diseases, and it is often misdiagnosed. Therefore, it is necessary to provide clinicians with clinical findings of patients with actinomycosis as many cases as possible. The aim of this study was to analyze the clinical features of actinomycosis of the orofacial soft tissues from the clinical data of the patients at the department in the past 10 years. Materials and methods A retrospective study was designed, and the general characteristics of the patients, and the clinical characteristics of actinomycosis, including the initial diagnoses, the treatment methods, and the treatment outcomes, were studied. Results Nine patients were included in the study. Initially, they were diagnosed with various diseases and treated by extraoral or intraoral surgical procedure with the administration of antibiotics. All patients were diagnosed with actinomycosis histopathologically, and lesions were cured. Conclusion The diagnoses of actinomycosis is often challenging. The histopathologic examination may provide the most valuable information for clinicians than any other examination. In most cases of actinomycosis of the orofacial soft tissues, clinicians should consider the methods of treatment along with the administration of penicillin because it is a chronic disease and usually has a good prognosis.

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Section: Discussionmentioning

confidence: 71%

Orofacial soft tissues actinomycosis: A retrospective, 10-year single-institution experience

Matsuda

Yoshida

Yoshimura

2021

Journal of Dental Sciences

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“…For example, a gingival inflammation, like the periodontal abscess and bone loss, is a fertile ground at local irritants, which permits the ingress into the gingival connective tissue of low virulent oral microflora [11]. In this frame, the result of some studies shows that a group of around 14-15 species of Actinomyces and especially Actinomyces Israeli, which is detected normally in oral flora, incriminates for increase of probability of PG [12]. Moreover, PG case reported in patient with Sturge-Weber Syndrome (SWS), or Encephalotrigeminal angiomatosis.…”

Section: Methodsmentioning

confidence: 99%

Pyogenic Granuloma: A Literature Review and A Case Report

Georgoulis

Zarenti

Anastasopoulos

et al. 2022

EJDENT

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Pyogenic granuloma of the oral cavity is a common, non-neoplastic, vascular tumor. The etiology is not clear and it is suggested to be attributed to different factors. It might be caused by a reaction to a stimulus such as trauma, viruses such as HSV-1, hormonal changes, as well as other factors such as tooth eruption or medication. Clinically it appears as a painless tumor that tends to bleed easily, with red color and rarely may be accompanied by a periodontal abscess and bone loss. Biopsy is the most common tool used for the diagnosis. Its treatment is usually surgical excision and lately the use of lasers for its excision has emerged. Special care should be given to pregnant women where the treatment varies. The aim of this review is to present the background of oral pyogenic granuloma and the case report presents the situation, histological image and treatment of an adult woman patient.

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“…Beside brucellosis, TB is not the only infectious disease to develop granulomas. Other intracellular bacteria known to develop this kind of structures are Coxiella burnetti (etiologic agent of the Q-fever) [ 206 ], Bartonella henselae (Cat-scratch disease) [ 207 ], Tropheryma whipplei (Whipple’s Disease) [ 208 ], Actinomyces israelii (actinomycosis) [ 209 ], and Salmonella enterica Typhimurium (gastroenteritis) [ 210 ], among others.…”

Section: Current Knowledge Of Immunosuppression and Chronicity Throug...mentioning

confidence: 99%

Immunosuppressive Mechanisms in Brucellosis in Light of Chronic Bacterial Diseases

2022

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Brucellosis is considered one of the major zoonoses worldwide, constituting a critical livestock and human health concern with a huge socio-economic burden. Brucella genus, its etiologic agent, is composed of intracellular bacteria that have evolved a prodigious ability to elude and shape host immunity to establish chronic infection. Brucella’s intracellular lifestyle and pathogen-associated molecular patterns, such as its specific lipopolysaccharide (LPS), are key factors for hiding and hampering recognition by the immune system. Here, we will review the current knowledge of evading and immunosuppressive mechanisms elicited by Brucella species to persist stealthily in their hosts, such as those triggered by their LPS and cyclic β-1,2-d-glucan or involved in neutrophil and monocyte avoidance, antigen presentation impairment, the modulation of T cell responses and immunometabolism. Attractive strategies exploited by other successful chronic pathogenic bacteria, including Mycobacteria, Salmonella, and Chlamydia, will be also discussed, with a special emphasis on the mechanisms operating in brucellosis, such as granuloma formation, pyroptosis, and manipulation of type I and III IFNs, B cells, innate lymphoid cells, and host lipids. A better understanding of these stratagems is essential to fighting bacterial chronic infections and designing innovative treatments and vaccines.

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Pyogenic granuloma associated with Actinomyces israelii

Cited by 4 publications

References 15 publications

Orofacial soft tissues actinomycosis: A retrospective, 10-year single-institution experience

Orofacial soft tissues actinomycosis: A retrospective, 10-year single-institution experience

Pyogenic Granuloma: A Literature Review and A Case Report

Immunosuppressive Mechanisms in Brucellosis in Light of Chronic Bacterial Diseases

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