Pyogenic liver abscess among children in a medical center in Central Taiwan

Hsu, Yu-Lung; Lin, Hsiao-Chuan; Yen, Ting‐Yu; Hsieh, Tsung-Hsueh; Wei, Hsiu-Mei; Hwang, Kao-Pin

doi:10.1016/j.jmii.2013.08.009

Cited by 29 publications

(55 citation statements)

References 6 publications

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“…2 The clinical features of pain and fever has also been noticed by others. 2 Male to female ratio was 1.4. Other studies have also found nearly same ratio.…”

Section: Discussionmentioning

confidence: 53%

Liver abscess in children: challenges in management

et al. 2017

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“…2 The clinical features of pain and fever has also been noticed by others. 2 Male to female ratio was 1.4. Other studies have also found nearly same ratio.…”

Section: Discussionmentioning

confidence: 53%

Liver abscess in children: challenges in management

et al. 2017

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“…Actually ultrasound was more widely used in clinical work due to universality of technology, ease of operation and higher cost performance, even as a tool to perform ultrasoundguild aspiration. It has been reported contrast-enhanced CT scan was done in PLA patients [16][17][18] , but owing to the potential risk of liver or renal function impaired and the consideration of economic burden, ultrasound became one of the main imaging examination method to diagnose PLA.…”

Section: Discussionmentioning

confidence: 99%

“…Culture-based techniques are the golden standard, and varies studies advanced more pathogens can be isolated through pus culture [18,20,21] . In our study the positive rate of blood or pus culture was not very high, it could be attribute to sample collection after prior antibiotic treatment of prehospitalization.…”

Section: Discussionmentioning

confidence: 99%

Clinical characteristics and pathogens of pediatric pyogenic liver abscess in Beijing Children’s Hospital, China

Xie¹,

Guo²,

Liu³

et al. 2020

Preprint

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Background: Data on pyogenic liver abscess (PLA) of children in China have been limited.Method: We retrospectively reviewed PLA cases from Hospital. Clinical features and pathogens were analyzed.Results: We diagnosed 15 PLA patients in our center. Median age of onset was 3.2 years and the median diagnostic time was 9 days. Four patients (26.7%) had underlying diseases and seven patients (46.7%) had multiple organ involvement. The sensitivity achieved 100% when ultrasound and contrast-enhanced CT scan were combined use to diagnose PLA. Two patients were defined pathogen through metagenomic next-generation sequencing (mNGS). Finally, eleven patients (73.3%) were cured during follow-up time and four patients (26.7%) dead. Compared to the survival group and the death group, the patients in death group were more likely to have multiple organ involved (100 vs. 27%, P < 0.05) and bilateral lobe occupied ( P < 0.05) .Conclusions: PLA often occurs in patients with underlying disease. Multiple organs involved may lead to poor prognosis. mNGS can be a new method to detect pathogen. HighlightsPyogenic liver abscess often occurs in patients with underlying disease.Multiple organs involved and bilateral lobe occupied may lead to poor prognosis.Metagenomic next-generation sequencing could be a new method to make diagnosis.

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“…Hsu et al 16) reported that fever and abdominal pain were the major manifestations of PLA. Other manifestations, such as diarrhea, vomiting, and weight loss are nonspecific.…”

Section: Discussionmentioning

confidence: 99%

Two cases of pyogenic liver abscess due to <i>Klebsiella pneumoniae</i> in immunocompetent children

Shin¹,

Lee²,

Hong³

et al. 2019

Pediatr Emerg Med J

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Pyogenic liver abscess (PLA) can be caused by bacteria entering the liver via the portal vein or primary bacteremia, or it can be cryptogenic. Recently, Klebsiella pneumoniae has been increasingly found as a PLA pathogen. PLA due to this bacterium often leads to formation of extrahepatic abscesses. The treatment of choice is dual therapy with insertion of percutaneous catheter drainage and antibiotic therapy. We report 2 cases of PLA due to K. pneumoniae in immunocompetent children. We successfully treated patient 1 with percutaneous catheter drainage for 18 days and 6-week course of antibiotic therapy. Patient 2 was treated with percutaneous needle aspiration and antibiotic therapy for the same period. In both patients, the PLAs showed the ultrasound-confirmed resolutions after the dual therapy.

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Pyogenic liver abscess among children in a medical center in Central Taiwan

Cited by 29 publications

References 6 publications

Liver abscess in children: challenges in management

Liver abscess in children: challenges in management

Clinical characteristics and pathogens of pediatric pyogenic liver abscess in Beijing Children’s Hospital, China

Two cases of pyogenic liver abscess due to <i>Klebsiella pneumoniae</i> in immunocompetent children

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