Pyosalpinx due to Cronobacter sakazakii in an elderly woman

Abstract

Background Cronobacter sakazakii (C. sakazakii) is a bacterium known to cause severe neonatal infections in premature infants with the consumption of contaminated powdered milk formula. Adult infections are rare, and there have been no reports of pyosalpinx due to C. sakazakii to date. Case presentation We report a case of left pyosalpinx due to C. sakazakii in a sexually inactive postmenopausal woman. A 70-year-old woman presented to our hospital with left lower abdominal pain and fever. Abdominal computed tomography disclosed a cystic mass continuous with the left edge of the uterus. Urgent laparotomy revealed a ruptured left pyosalpinx with pus-like content. Left salpingo-oophorectomy, resection of the right tube, and washing of the abdominal cavity with saline were performed. Pathological examination of the left adnexa showed tubal tissue with acute inflammation and inflammatory exudate, which were compatible with pyosalpinx, and pus culture yielded C. sakazakii. Conclusions This is the first case report of pyosalpinx due to C. sakazakii. Cronobacter sakazakii infections in adult women might occur in the elderly, whose immunity has weakened. Further accumulation of cases of C. sakazakii infection is needed to clarify the etiology and behavior of C. sakazakii in adults.

Acute obstructive pyelonephritis due to pyosalpinx: a case report

“…Pyosalpinx is defined as purulent intratubal collections, which may occur de novo or by ascending infection of a hydrosalpinx. Therefore, pyosalpinx and tubo-ovarian abscess are usually observed in young women; they are rarely found in older women [ 3 ]. In the literature, 194 cases of pyosalpinx or tubo-ovarian abscess in postmenopausal woman have been reported [ 3 , 4 ].…”

“…Therefore, pyosalpinx and tubo-ovarian abscess are usually observed in young women; they are rarely found in older women [ 3 ]. In the literature, 194 cases of pyosalpinx or tubo-ovarian abscess in postmenopausal woman have been reported [ 3 , 4 ]. Pyosalpinx may present with very few specific symptoms or remain silent [ 5 ].…”

Current and Future Perspectives on the Role of Probiotics, Prebiotics, and Synbiotics in Controlling Pathogenic Cronobacter Spp. in Infants

“…In one outbreak involving high school students, for example, C. sakazakii was isolated from leftover cafeteria food and resulted in acute gastroenteritis in 156 individuals ( Yong et al, 2018 ). Overall, the sources of C. sakazakii infection in adults and the elderly are unclear as the foodborne pathogen can be found in a wide range of environmental sources including plant and animal-derived foods, sewer water, and dust ( Tsai et al, 2013 ; Yong et al, 2018 ; Ohira et al, 2021 ).…”

Proteomic Analysis Revealed Metabolic Inhibition and Elongation Factor Tu Deamidation by p-Coumaric Acid in Cronobacter sakazakii

“…This microbe is ubiquitous in the environments and is often isolated from water, soil, kitchens, vegetables, and a variety of food samples, including powdered infant formula ( Mohammed et al, 2015 ; Li et al, 2016 ; Henry and Fouladkhah, 2019 ). Cronobacter sakazakii infections can occur in all age groups, and most, though usually not serious, infections occur in adults ( Kadlicekova et al, 2018 ; Holý et al, 2019 ; Ohira et al, 2021 ). Nevertheless, immunocompromised patients, as well as premature, low-birth-weight babies were considered at higher risk ( Stoll et al, 2004 ).…”