Pyridoxamine driven selective turn-off detection of picric acid using glutathione stabilized fluorescent copper nanoclusters and its applications with chemically modified cellulose strips

Patel, R. J.; Bothra, Shilpa; Kumar, Rajender; Crisponi, Guido; Sahoo, Suban K.

doi:10.1016/j.bios.2017.11.031

Cited by 81 publications

(20 citation statements)

References 36 publications

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“…Ravi et al (Patel et al 2018) found that pyridoxamine (PM) could specifically interact with GSH-CuNCs and thus adsorb to their surfaces, resulting in the formation of a new band near 410 nm in the fluorescence spectra. However, the addition of picric acid quenched the fluorescence both at 410 nm and 625 nm with high efficiency and selectivity (Fig.…”

Section: Picric Acid (Pa) Detectionmentioning

confidence: 99%

Highly fluorescent copper nanoclusters for sensing and bioimaging

Ren

Bick

et al. 2020

Biosensors and Bioelectronics

155

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Metal nanoclusters (NCs), typically consisting of a few to tens of metal atoms, bridge the gap between organometallic compounds and crystalline metal nanoparticles. As their size approaches the Fermi wavelength of electrons, metal NCs exhibit discrete energy levels, which in turn results in the emergence of intriguing physical and chemical (or physicochemical) properties, especially strong fluorescence. In the past few decades, dramatic growth has been witnessed in the development of different types of noble metal NCs (mainly AuNCs and AgNCs). However, compared with noble metals, copper is a relatively earth-abundant and cost-effective metal. Theoretical and experimental studies have shown that copper NCs (CuNCs) possess unique catalytic and photoluminescent properties. In this context, CuNCs are emerging as a new class of nontoxic, economic, and effective phosphors and catalysts, drawing significant interest across the life and medical sciences. To highlight these achievements, this review begins by providing an overview of a multitude of factors that play central roles in the fluorescence of CuNCs. Additionally, a critical perspective of how the aggregation of CuNCs can efficiently improve the florescent stability, tunability, and intensity is also discussed. Following, we present representative applications of CuNCs in detection and bioimaging. Finally, we outline current challenges and our perspective on the development of CuNCs.When decreasing the size of nanoparticles so that it approaches the Fermi wavelength of an electron, novel optical, electrical and magnetic properties appear (Deng et al. 2018a; Li et al. 2016b;Moghadam and Rahaie 2019;Wang et al. 2018c). Commonly termed nanoclusters (NCs), these ultra-small nanoparticles, bridging the missing link between atoms and nanocrystals, have attracted considerable attention in both fundamental research and practical applications (Bagheri et al. 2017;Basu et al. 2019;Sun et al. 2019;Wang et al. 2016b). Benefiting from the great progress in nanosynthetic chemistry, high-quality Copper NCs (CuNCs) with tailored size and good stability can be easily obtained. CuNCs, therefore, constitute an active research direction due to their unique properties, such as high luminous efficiency, long fluorescence lifetime, good optical and chemical stability, and large stokes displacement, which distinguish them as a new type of fluorescent probe for optical sensing and bioimaging/labeling (Cao et al. 2014;Wang et al. 2017).In this review, we highlight recent developments of CuNCs, with a particular emphasis on the multiple factors affecting fluorescent properties of CuNCs, as well as the aggregation-induced emission enhancement (AIEE) effect. To appreciate these advances, applications focused on the detection of ions, macromolecules and bioimaging are summarized. Lastly, we will provide a brief conclusion, and will address future challenges in the rapidly growing field of fluorescent CuNCs. Multiple factors that govern the fluorescence of CuNCsDue to the size of CuNCs falls w...

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Section: Picric Acid (Pa) Detectionmentioning

confidence: 99%

Highly fluorescent copper nanoclusters for sensing and bioimaging

Ren

Bick

et al. 2020

Biosensors and Bioelectronics

155

View full text Add to dashboard Cite

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“…Also, the absence of any satellite peak in the region close to 942 eV confirms the reduction of Cu 2+ by GSH. 34 The deconvoluted XPS spectrum of S 2p showed three characteristic signals at 161.0, 162.6, and 163.8 eV for the oxidized sulfur, Cu−S and S, respectively. The S 2p XPS spectrum supported the functionalization GSH over the CuNCs through the S atom.…”

Section: Resultsmentioning

confidence: 95%

Cascade Detection of Pyridoxal 5′-Phosphate and Al³⁺ Ions Based on Dual-Functionalized Red-Emitting Copper Nanoclusters

Bhardwaj

Bothra

Upadhyay

et al. 2021

ACS Appl. Nano Mater.

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Pyridoxal 5′-phosphate (PLP), a biologically important coenzyme, participates in several enzymatic reactions, and its marginal deficiency in the human body can cause cardiovascular disease. However, the excess accumulation of the non-essential Al3+ metal ion in the human body can also cause serious health problems. Therefore, there is significant interest in the detection and monitoring of both PLP and Al3+. This paper introduced a red-emitting dual-ligand co-functionalized copper nanoclusters β-CD-GSH-CuNCs for the simultaneous detection of PLP and Al3+. The capped β-cyclodextrin (β-CD) in β-CD-GSH-CuNCs selectively recognizes PLP by forming a host–guest inclusion complex that caused fluorescence quenching at 625 nm with the formation of an emission band at 488 nm. The ratiometric fluorescence from β-CD-GSH-CuNCs allowed to detect PLP down to 5.29 μM. Further, the in situ-generated nano-assembly β-CD-GSH-CuNCs@PLP showed a selective turn-on fluorescent response for Al3+. The complexation-induced aggregation of nano-assembly resulted in strong fluorescence enhancement at 451 nm that allowed to detect Al3+ down to 0.187 μM. The analytical utility of β-CD-GSH-CuNCs@PLP was validated as a nanoprobe by monitoring Al3+ concentrations in real environmental water samples.

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“…Many research groups developed GSH capped Cu NCs with orange or red fluorescence emission [ 36 , 37 , 38 ]. A one-pot sonochemical synthesis method was established for the preparation of GSH-Cu NCs by Wang et al [ 39 ].…”

Section: Preparation Methods and Sensing Mechanism Of Cu Ncsmentioning

confidence: 99%

“…Similarly, there has also been an urgent need for the facile and sensitive detection of picric acid (2,4,6- trinitrophenol, PA). Patel et al [ 37 ] reported an analytical system for PA based on the fluorescence quenching of glutathione stabilized copper nanoclusters and a vitamin B6 cofactor pyridoxamine (PM-GSH-Cu NCs) ( Figure 7 b). This nanoprobe exhibited excellent sensitivity and selectivity to PA in different solutions and real samples including tap water, river water and matchstick.…”

Section: Sensing Applications Based On Cu Ncsmentioning

confidence: 99%

Synthesis of Copper Nanocluster and Its Application in Pollutant Analysis

et al. 2021

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Copper nanoclusters (Cu NCs) with their inherent optical and chemical advantages have gained increasing attention as a kind of novel material that possesses great potential, primarily in the use of contaminants sensing and bio-imaging. With a focus on environmental safety, this article comprehensively reviews the recent advances of Cu NCs in the application of various contaminants, including pesticide residues, heavy metal ions, sulfide ions and nitroaromatics. The common preparation methods and sensing mechanisms are summarized. The typical high-quality sensing probes based on Cu NCs towards various target contaminants are presented; additionally, the challenges and future perspectives in the development and application of Cu NCs in monitoring and analyzing environmental pollutants are discussed.

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Pyridoxamine driven selective turn-off detection of picric acid using glutathione stabilized fluorescent copper nanoclusters and its applications with chemically modified cellulose strips

Cited by 81 publications

References 36 publications

Highly fluorescent copper nanoclusters for sensing and bioimaging

Highly fluorescent copper nanoclusters for sensing and bioimaging

Cascade Detection of Pyridoxal 5′-Phosphate and Al³⁺ Ions Based on Dual-Functionalized Red-Emitting Copper Nanoclusters

Synthesis of Copper Nanocluster and Its Application in Pollutant Analysis

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Pyridoxamine driven selective turn-off detection of picric acid using glutathione stabilized fluorescent copper nanoclusters and its applications with chemically modified cellulose strips

Cited by 81 publications

References 36 publications

Highly fluorescent copper nanoclusters for sensing and bioimaging

Highly fluorescent copper nanoclusters for sensing and bioimaging

Cascade Detection of Pyridoxal 5′-Phosphate and Al3+ Ions Based on Dual-Functionalized Red-Emitting Copper Nanoclusters

Synthesis of Copper Nanocluster and Its Application in Pollutant Analysis

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Cascade Detection of Pyridoxal 5′-Phosphate and Al³⁺ Ions Based on Dual-Functionalized Red-Emitting Copper Nanoclusters