Pyrrolidinyl peptide nucleic acids immobilised on cellulose paper as a DNA sensor

Abstract

“Immobilisation of pyrrolidinyl peptide nucleic acids on paper resulted in a new DNA sensor with great specificity”.

Nanobioengineered Sensing Technologies Based on Cellulose Matrices for Detection of Small Molecules, Macromolecules, and Cells

“…The resulting intensity of the biosensor was found to be linearly proportional to the amount of Bilirubin present in the sample with a detection range of 2 to 20 mg dL −1 . [83]). (B) Surface tethering of the cellulose-based sensor for the identification of Esterase enzyme by using the flu orogen (reproduced with permission from [90]).…”

“…(B) Surface tethering of the cellulose-based sensor for the identification of Esterase enzyme by using the flu orogen (reproduced with permission from [90]). (C) Illustration of bilirubin sensor using photoluminescent carbon dot sensing probes (reproduced with permission (D-prolyl-2-aminocyclopentanecarboxylic acid-peptide nucleic acid) through covalent bonding on the cellulose paper and cationic dye Azure A is used for signal detection (reproduced with permission from [83]). (B) Surface tethering of the cellulose-based sensor for the identification of Esterase enzyme by using the flu orogen (reproduced with permission from [90]).…”

“…A cellulose paper-based sensor has been fabricated for the visual detection of DNA by Jirakittiwut et al, 2015. The biosensor was developed by immobilization of acpc PNA (D-prolyl-2-aminocyclopentane-carboxylic acid PNA) on cellulose paper by divinyl sulfone-mediated conjugation [ 83 ]. PNA is an artificial mimic of the DNA that acts as a probe for the sensing of DNA.…”

“… Biosensors for detection of macromolecules. ( A ) Fabrication of DNA sensor by immobilization of acpc PNA (D-prolyl-2-aminocyclopentanecarboxylic acid—peptide nucleic acid) through covalent bonding on the cellulose paper and cationic dye Azure A is used for signal detection (reproduced with permission from [ 83 ]). ( B ) Surface tethering of the cellulose-based sensor for the identification of Esterase enzyme by using the flu orogen (reproduced with permission from [ 90 ]).…”

Layer-by-layer assembled protein nanotubes with high DNA affinity

“…The adsorption or immobilization of nucleic acid on solid surfaces is essential in a wide range of research including DNA chip technology, DNA hybridization and gene delivery. [1][2][3][4][5][6] The inherent merits of nanotubes, for example, unique hollow structure, distinct inner and outer surfaces as well as two open-end terminals, make it to a promising nanomaterial for bimolecular immobilization and delivery. 7 Inorganic nanotubes such as carbon nanotubes, 8 silica nanotubes 9 and magnetic nanotubes 10 have been developed for gene vectors.…”