2021
DOI: 10.1016/j.anifeedsci.2021.115062
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Pyrrolizidine alkaloids of European Senecio/Jacobaea species in forage and their carry-over to milk: A review

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Cited by 9 publications
(7 citation statements)
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“…Carry over to milk is a further problem of PAs in animal nutrition. [38] In experiments feeding cows with 200 g a day Senecio plants, PA concentrations of 9.7 μg/L or 12.1 μg/L have been reported in the obtained milk. [40,41] With the BMDL 10 mentioned above and a MOE (margin of exposure) greater than 10,000 a person should not consume more than 0.0237 μg/kg body weight or roughly 1.5 μg per day (for a person of 60 kg).…”
Section: Discussionmentioning
confidence: 99%
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“…Carry over to milk is a further problem of PAs in animal nutrition. [38] In experiments feeding cows with 200 g a day Senecio plants, PA concentrations of 9.7 μg/L or 12.1 μg/L have been reported in the obtained milk. [40,41] With the BMDL 10 mentioned above and a MOE (margin of exposure) greater than 10,000 a person should not consume more than 0.0237 μg/kg body weight or roughly 1.5 μg per day (for a person of 60 kg).…”
Section: Discussionmentioning
confidence: 99%
“…Horses are the most sensitive animals. Among the ruminants, the susceptibility decreases from cattle to goats and to sheep [38] . As the alkaloid contents of the plants and duration of toxic plant intake are too variable [7] it is difficult to perform a reliable risk assessment.…”
Section: Discussionmentioning
confidence: 99%
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“…Hence, removing the ragwort-infested biomass is necessary to avoid sward degradation and to enhance the biodiversity of the infested grasslands. However, the traditional use of conservation growths, such as forage for livestock, is often not possible due to its PA contamination [ 32 , 33 , 34 ]. Therefore, there is an urgent need for a sustainable and safe use of the contaminated biomass apart from disposing of it as landfill.…”
Section: Introductionmentioning
confidence: 99%