QRS duration and prediction of mortality in patients undergoing risk stratification for ventricular arrhythmias

Kalahasti, Vidyasagar; Nambi, Vijay; Martin, David O.; Lam, Charlene; Yamada, David; Wilkoff, Bruce L.; Niebauer, Mark; Jaeger, Fredrick J.; Tchou, Patrick; Chung, Mina K.

doi:10.1016/s0002-9149(03)00886-5

Cited by 65 publications

(28 citation statements)

References 16 publications

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“…However, the exclusion criteria for the current study, which precluded patients with LVEF < 30% from participating, prevented an investigation into the mediating role of low LVEF in this sample. This finding that CAD severity may be more strongly associated with VPBs than LVEF is consistent with previous research showing that the relatively higher risk of mortality associated with LV dysfunction may be mediated by CAD severity (23).…”

Section: Discussionsupporting

confidence: 92%

Ventricular ectopy: Impact of self-reported stress after myocardial infarction

Smith¹,

Blumenthal²,

Babyak³

et al. 2007

American Heart Journal

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Section: Discussionsupporting

confidence: 92%

Ventricular ectopy: Impact of self-reported stress after myocardial infarction

Smith¹,

Blumenthal²,

Babyak³

et al. 2007

American Heart Journal

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“…For every 10 ms increase in QRS duration, mortality rate increased 10%. 41 These results are supported by findings from the Ventak CHF BiV pacing study, where the frequency of defibrillation therapy has been evaluated. 42 At least one tachyarrhythmic episode was documented in 5/32 patients(16%) during BiV pacing, whereas 11 (34%) had at least one episode while programmed to no pacing.…”

Section: Ventricular Arrhythmiamentioning

confidence: 61%

Established and evolving indications for cardiac resynchronisation

Nesser

2004

Heart

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“…Kalahasti et al [11] found that prolonged QRS duration was a strong independent marker of long-term mortality. The duration of QRS was also a predictor of the clinical outcome of heart failure in implantable cardioverter defibrillator recipients [12].…”

Section: Discussionmentioning

confidence: 99%

Parameters associated with one-year mortality and in-hospital adverse events in patients after emergency pacemaker implantation

et al. 2016

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A b s t r a c tBackground: Permanent cardiac pacing is the treatment of choice for severe and symptomatic bradycardia. Patients undergoing emergency pacemaker implantation are stabilised earlier by the insertion of a temporary emergency pacing lead, and they experience more comorbidities than with planned admissions. Aim:To identify the parameters associated with one-year mortality and in-hospital adverse events after emergency permanent pacemaker implantation. Methods:This retrospective study analyses data from 131 consecutive emergency pacemaker implantations performed within a single centre. Results:Cox regression analysis revealed the independent predictors of death to be: use of a temporary transvenous pacing lead (TTPL) (HR = 2.82, 95% CI 1.21-6.58, p = 0.02), age ≥ 78 years (OR = 3.01, 95% CI 1.22-7.42, p = 0.02), longer baseline QRS duration (HR = 1.02, 95% CI 1.00-1.03, p = 0.03), and history of myocardial infarction (MI) (HR = 2.43, 95% CI 1.04-5.68, p = 0.04). Twenty-six patients experienced in-hospital adverse events, such as: death (n = 6), cardiac arrest (n = 3), surgical complications (lead dislocation: n = 4, haematoma: n = 4, microperforation: n = 2), pneumonia or respiratory tract disease (n = 7), wound infection treated with antibiotics (n = 1), and subsequent MI following pacemaker implantation (n = 2). Multivariate logistic regression analysis showed that independent parameters associated with in-hospital adverse events were history of MI (OR = 5.01, 95% CI 1.88-13.3, p = 0.001) and stroke (OR = 3.51, 95% CI 1.16-10.55, p = 0.03). Conclusions:Our results suggest that the most serious risk factors of one-year mortality related to the use of TTPL are: age ≥ 78 years, longer baseline QRS duration, and history of MI. The independent parameters associated with in-hospital adverse events were the presence of a history of MI and stroke.

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QRS duration and prediction of mortality in patients undergoing risk stratification for ventricular arrhythmias

Cited by 65 publications

References 16 publications

Ventricular ectopy: Impact of self-reported stress after myocardial infarction

Ventricular ectopy: Impact of self-reported stress after myocardial infarction

Established and evolving indications for cardiac resynchronisation

Parameters associated with one-year mortality and in-hospital adverse events in patients after emergency pacemaker implantation

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