Qualidade de vida relacionada à saúde em pacientes com lúpus eritematoso sistêmico no Centro-Oeste do Brasil

Abstract

Introduction/Objective: Evaluate the quality of life (QOL) of women with systemic lupus erythematosus (SLE) and the association between QOL domains, measured by the World Health Organization Quality of Life Group (WHOQOL-100) assessment instrument, and disease activity. Patients and Methods: A cross-sectional analytic study involving 95 patients with SLE, according to the American College of Rheumatology (ACR) criteria, aged 20-49 years, attended at the University Center of Universidade Federal de Mato Grosso do Sul, Campo Grande, MS. We used the following instruments: demographic and clinical data collection form and WHOQOL-100 instrument. Evaluation of disease activity was performed by SLEDAI. On statistical analysis, we applied Student's t-test, ANOVA, and Pearson's correlation. Results: Group-case: 79 female with mild to moderate SLE activity (SLEDAI = 1-10) and severe activity (SLEDAI ≥ 11). Control group: 16 female with inactive SLE (SLEDAI = 0). All domains of WHOQOL-100 proved to be affected, with significant difference (P < 0.005) between the case and control groups in which there was a better perception of QOL in the domain Spirituality and worst perception of QOL in the domain Environment. When confronting QOL domains with education, we detected a significant difference (P < 0.05) in the Physical, Psychological, Level of independence, and Environment domains. The comparison between QOL and disease activity was significant (P < 0.005) in three domains: Physical, Psychological, and Environment. Conclusion: SLE with intense activity determines a worse QOL condition than inactive SLE. The assessment of QOL enables the knowledge of disease and treatment impact in a contextualized way, which can render more appropriate and more comprehensive interventions.

The systemic lúpus erythematosus and women's selfimage carrier / O lúpus eritematoso sistêmico e a autoimagem da mulher portadora / El lupus eritematoso sistémico y el portadora autoimagen de las mujeres

“…O efeito de todas as alterações causadas no decorrer da doença e o tratamento no sentido clínico da mesma exige medidas que beneficiem a qualidade de vida como ferramenta primordial de satisfação para as pacientes. As portadoras de LES que determinam uma adoção de estratégias cognitivas e comportamentais de melhor enfrentamento das situações apresentam melhores níveis de recuperação da doença, pois elas deslocam o foco dos problemas emocionais (5) .…”

“…Em pessoas com LES, a qualidade de vida é prejudicada em comparação com a população em geral. O prejuízo se deve às alterações físicas e emocionais ocasionadas pelo processo patológico, especialmente nos períodos de exacerbação do LES (5) .…”

Diálogos Entre Espiritualidade E Enfermagem: Uma Revisão Integrativa Da Literatura

“…Sendo assim, o momento de luto, o qual constitui um momento de intensa dor, constitui um objeto de ação da espiritualidade (12)(13) . (14)(15)(16)(17) . Percebe-se, também, que o exercício da espiritualidade pode ser um grande aliado no que se refere ao processo de reabilitação quanto ao abuso e dependência de álcool e outras drogas (18)(19)(20) .…”

The importance of resilience for treatment adhesion in patients with systemic lupus erythematosus

“…19 The literature reports indicate that most of the symptoms of SLE interfere with several aspects of the patient´s life, which may lead to abandoning of regular employment and daily activities. 20,[43][44][45] However, RS may be a contributing factor that assists patients manage or alter their lifestyle, and maintain an efficacious performance in daily activities, in spite of the adversities or stress. 23,24,32 In SLE, treatment adhesion is a determinant factor for absence of disease activity and not receiving the medication is an important cause of non-adhesion.…”