Quality control of flavonoids in Ginkgo biloba leaves by high-performance liquid chromatography with diode array detection and on-line radical scavenging activity detection

Ding, Xuehua; Qi, Jin; Chang, Yan‐xu; Mu, Lingli; Zhu, Daling; Yu, Boyang

doi:10.1016/j.chroma.2008.08.115

Cited by 77 publications

(54 citation statements)

References 29 publications

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“…Based on the experimental conditions described above, flavonoids extracted from -146-146-162+H] + was supposed as after the loss of two rhamosyl groups and a glucosyl group. These ESI-MS data matched with isorhamnetin3-O-(2, 6-dirhamnosyl)glucoside (Sakushima et al 1980;Mauri & Pietta 2000;Ding et al 2009). …”

Section: Identification Of the Main Flavonoidsmentioning

confidence: 81%

Extraction, purification, and characterisation of the flavonoids from Opuntia milpa alta skin

Cai¹,

Gu²,

Tang³

2010

Czech J. Food Sci.

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Cai W., Gu X., Tang J. (2010): Extraction, purification, and characterisation of the flavonoids from Opuntia milpa alta skin. Czech J. Food Sci., 28: 108-116.The flavonoids contained in Opuntia milpa alta skin were extracted, purified, and identified. Based on single factor experimental results, the extraction parameters were optimised by using orthogonal design and variance analysis. The results show that the maximum yield of the flavonoids (5.55 mg/g dry weight) can be obtained with 80% ethanol (v/v), extraction temperature of 90°C, and the solvent to raw material ratio of 25:1. After purification with AB-8 resin, the main components of the extract were characterised as isorhamnetin 3-O-(2, 6-dirhamnosyl)glucoside and isorhamnetin 3-O-d-rutinoside by employing liquid chromatography-mass spectrometry and ultraviolet-visible spectrometry.

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Section: Identification Of the Main Flavonoidsmentioning

confidence: 81%

Extraction, purification, and characterisation of the flavonoids from Opuntia milpa alta skin

Cai¹,

Gu²,

Tang³

2010

Czech J. Food Sci.

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“…22 In another study, the authors studied GB leaves with high-performance liquid chromatography and indicated that flavonoids in GB had powerful antioxidant attributes. 23 Gingko biloba bilobalide plays a crucial role in mitochondrial protection during ischemia. Bilobalide allows the mitochondria to maintain respiratory activity at decreased oxygen levels, which delays ischemia-induced injury.…”

Section: Discussionmentioning

confidence: 99%

The protective effect of Gingko biloba in a rat model of ovarian ischemia/reperfusion injury: Improvement in histological and biochemical parameters

et al. 2018

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“…biloba is one of the most popular medicinal plants. Active compounds in Ginkgo extract possess antioxidant [1][2][3], antiasthmatic [4], and wound-healing properties [5], improve blood circulation, discourage clot formation, reinforce the walls of capillaries, and protect nerve cells from harm when deprived of oxygen [6]. Due to its notable pharmacological effects, G. biloba is widely used for the treatment of Alzheimer's disease [7], concentration difficulties, and memory impairment [8], cerebral insufficiency [9], intermittent claudication [10], vertigo [11], and tinnitus [12].…”

Section: Introductionmentioning

confidence: 99%

Variation in Flavonoid Composition and Radical-Scavenging Activity inGinkgo bilobaL. due to the Growth Location and Time of Harvest

Rimkienė

Kubilienė

Ževžikovas

et al. 2017

Journal of Food Quality

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The aim of our research is to investigate the qualitative and quantitative composition and antioxidant activity of flavonoids in leaf samples of Ginkgo biloba L. (G. biloba) growing in Lithuania and also to provide practical recommendations for the pharmaceutical industry to determine the optimum harvesting time and growth location of G. biloba leaves. The obtained results indicate that the growth location and time of sample collection have a significant influence ( ≤ 0.05) on the content of active compounds. July and August are the best months to harvest G. biloba leaves for industry. To ensure the rational collection of G. biloba raw material, the location of plantations is recommended in the western and southwestern phytoregions. The obtained results also indicate that the flavonoid content in G. biloba leaf has a significantly positive correlation ( = 0.952, ≤ 0.001) with antioxidant activity. The aqueous acetonic extracts from green leaves scavenge radicals to a greater degree than those from yellow Ginkgo leaves. The results of this investigation provide information regarding the most suitable Lithuanian growing location to produce G. biloba with an optimized content of health-promoting compounds.

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Quality control of flavonoids in Ginkgo biloba leaves by high-performance liquid chromatography with diode array detection and on-line radical scavenging activity detection

Cited by 77 publications

References 29 publications

Extraction, purification, and characterisation of the flavonoids from Opuntia milpa alta skin

Extraction, purification, and characterisation of the flavonoids from Opuntia milpa alta skin

The protective effect of Gingko biloba in a rat model of ovarian ischemia/reperfusion injury: Improvement in histological and biochemical parameters

Variation in Flavonoid Composition and Radical-Scavenging Activity inGinkgo bilobaL. due to the Growth Location and Time of Harvest

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