Quality Control Process for EQ-5D-5L Valuation Studies

Ramos-Goñi, Juan Manuel; Oppe, Mark; Slaap, Bernhard; Busschbach, Jan J. V.; Stolk, Elly

doi:10.1016/j.jval.2016.10.012

Cited by 139 publications

(140 citation statements)

References 20 publications

Supporting

Mentioning

136

Contrasting

Order By: Relevance

“…They were then asked to confirm their choices or to identify which of the health states they considered to be incorrectly ranked. The number of inconsistencies were reported and were used in the quality control process [21].…”

Section: Interview Processmentioning

confidence: 99%

A French Value Set for the EQ-5D-5L

et al. 2020

Self Cite

View full text Add to dashboard Cite

Objective The objective of this study was to develop a French value set for the EQ-5D-5L, for academic and clinical research, and for regulatory requirements for price-setting of drugs and medical devices. Method This study used the standardized valuation protocol developed by EuroQol, using computer-assisted personal interview software. A representative sample of 1048 French residents were interviewed by a market research company, under the supervision of the research team. Health states were valued using composite time trade-off and a discrete choice experiment. Modeling was used to create values for the 3125 possible health states. The composite time trade-off data were modeled using a Tobit model with censored observations at −1 and correcting for heteroscedasticity. A conditional logit model was used for the discrete choice results, and both models were combined using a hybrid model. An adjusted hybrid model was tested to correct for imbalance in the sample on age and sex compared with the general population. A comparison with the 3-level (3L) value set was performed. Results The adjusted model was preferred to comply with the representativeness of the general population. It provided a value set for which all coefficients were logically consistent. Values ranged from − 0.525 to 1. The distribution of values presented a shift towards higher values versus the 3L value set. Ranking of dimensions changed. Pain and discomfort and mobility were the dimensions with the highest potential for disutility compared with mobility and self-care for the 3L instrument. Conclusions This study provides a value set based on societal preferences of the French population, using an improved descriptive instrument of health-related quality-of-life health states. It will contribute to improve the quality of cost-effectiveness analysis in the French context and help stimulate disease-specific quality-of-life references for academic-, institutional-, and industry-promoted studies.

show abstract

Section: Interview Processmentioning

confidence: 99%

A French Value Set for the EQ-5D-5L

et al. 2020

Self Cite

View full text Add to dashboard Cite

show abstract

“…Interviewers were also required to follow a set protocol for the different study arms. A quality control process using the EQ-VT QC tool was implemented to ensure protocol compliance [33].…”

Section: Data Collectionmentioning

confidence: 99%

Valuation of EuroQol Five-Dimensional Questionnaire, Youth Version (EQ-5D-Y) and EuroQol Five-Dimensional Questionnaire, Three-Level Version (EQ-5D-3L) Health States: The Impact of Wording and Perspective

et al. 2018

Self Cite

View full text Add to dashboard Cite

Background: Valuations of health states were affected by the wording of the two instruments (EQ-5D-3L and EQ-5D-Y) and by the perspective taken (child or adult). Objectives: There is a growing demand for value sets for the EQ-5D-Y (EQ-5D instrument for younger populations). Given the similarities between EQ-5D-Y and EQ-5D-3L, we investigated whether valuations of health states were affected by the differences in wording between the two instruments and by the perspective taken in the valuation exercise (child or adult). Study Design: Respondents were randomly assigned to EQ-5D-3L or EQ-5D-Y (instrument) and further into two groups that either valued health states for an adult or for a 10-year-old child (perspective). The valuation tasks were composite time trade-off (C-TTO) and discrete choice experiments (DCE), including comparisons with death (DCE þ death). Members of the adult general population in four countries (Germany, Netherlands, Spain, England) participated in computer-assisted personal interviews. Methods: Two-way multivariate analysis of variance (MANOVA) and post hoc tests were used to compare C-TTO responses and chisquare tests were conducted to compare DCE þ death valuations. Results: A significant interaction effect between instrument and perspective for C-TTO responses was found. Significant differences by perspective (adult and child) occurred only for the EQ-5D-3L. Significant differences in values between instruments (EQ-5D-3L and EQ-5D-Y) occurred only for the adult perspective. Both significant results were confirmed by the DCE þ death results. When comparing EQ-5D-3L for adult perspective and EQ-5D-Y for child perspective, values were also significantly different. Conclusions: The results identified an interaction effect between wording of the instrument and perspective on elicited values, suggesting that current EQ-5D-3L value sets should not be employed to assign values to EQ-5D-Y health states.

show abstract

“…14 Upon publication of the EQ-5D-5L descriptive system, an interim crosswalk was developed to facilitate the generation of preference-based summary scores on the basis of EQ-5D-5L responses. 15 The EuroQol Group invested in a scientific program that examined alternative approaches to preference elicitation, 16,17 developed methods to improve data quality, 18 and demonstrated the robustness of these approaches across countries and languages. 19 The accumulation of evidence supported a standardized valuation protocol implemented in software named the EuroQol Valuation Technology (EQ-VT).…”

Section: Introductionmentioning

confidence: 99%

“…[24][25][26][27][28] The EQ-VT has been shown to improve data quality and minimize interviewer effects. 18,29 Building on this evidence to apply a standardized approach to a national value set, the aim of this study was to estimate a value set for the EQ-5D-5L that will support economic evaluation of healthcare interventions in the United States; by using an internationally established protocol, the US value set will also facilitate cross-country comparisons.…”

Section: Introductionmentioning

confidence: 99%

United States Valuation of EQ-5D-5L Health States Using an International Protocol

et al. 2019

Self Cite

View full text Add to dashboard Cite

A B S T R A C TObjective: To derive a US-based value set for the EQ-5D-5L questionnaire using an international, standardized protocol developed by the EuroQol Group.Methods: Respondents from the US adult population were quota-sampled on the basis of age, sex, ethnicity, and race. Trained interviewers guided participants in completing composite time trade-off (cTTO) and discrete choice experiment (DCE) tasks using the EuroQol Valuation Technology software and routine quality control measures. Data were modeled using a Tobit model for cTTO data, a mixed logit model for DCE data, and a hybrid model that combined cTTO and DCE data. Model performance was compared on the basis of logical ordering of coefficients, statistical significance, parsimony, and theoretical considerations.Results: Of 1134 respondents, 1062, 1099, and 1102 respondents provided useable cTTO, DCE, and cTTO or DCE responses, respectively, on the basis of quality control criteria and interviewer judgment. Respondent demographic characteristics and health status were similar to the 2015 US Census. The Tobit model was selected as the preferred model to generate the value set. Values ranged from 20.573 (55 555) to 1 (11111), with 20% of all predicted health states scores less than 0 (ie, worse than dead). Conclusions:A societal value set for the EQ-5D-5L was developed that can be used for economic evaluations and decision making in US health systems. The internationally established, standardized protocol used to develop this US-based value set was recommended by the EuroQol Group and can facilitate cross-country comparisons.

show abstract

Quality Control Process for EQ-5D-5L Valuation Studies

Abstract: The implementation of a strict QC process in EQ-5D-5L valuation studies increases interviewer protocol compliance and promotes data quality.

Cited by 139 publications

References 20 publications

A French Value Set for the EQ-5D-5L

A French Value Set for the EQ-5D-5L

Valuation of EuroQol Five-Dimensional Questionnaire, Youth Version (EQ-5D-Y) and EuroQol Five-Dimensional Questionnaire, Three-Level Version (EQ-5D-3L) Health States: The Impact of Wording and Perspective

United States Valuation of EQ-5D-5L Health States Using an International Protocol

Contact Info

Product

Resources

About