Ineffective handoff communication is a recognized patient safety risk in health care. In response, quality improvement experts have developed methods for structuring and standardizing transfer processes and handoff communication. These have included mnemonics for use during handovers, scripts or worksheets for the standardization of information conveyed, and the minimization of interruptions and distractions during verbal handovers. [1][2][3][4] Recent studies have also reported successfully leveraging multidisciplinary team strategies and workflow adjustments, such as reducing nighttime transfers from the ICU. 5 Most notably, the implementation of the I-PASS (illness severity, patient summary, action list, situation awareness and contingency plans, and synthesis by receiver)-supported handoff bundle studied with resident-to-resident handoffs has abstract BACKGROUND AND OBJECTIVES: Recent publications have shown improved outcomes associated with resident-to-resident handoff processes. However, the implementation of similar handoff processes for patients moving between units and teams with expansive responsibilities presents unique challenges. We sought to determine the impact of a multidisciplinary standardized handoff process on efficiency, safety culture, and satisfaction.