Quality of consumer drug information provided by four Web sites

Hatfield, Catherine L.; May, Sondra K.; Markoff, Jeffrey S.

doi:10.1093/ajhp/56.22.2308

Cited by 28 publications

(21 citation statements)

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“…However, with the ever-expanding plethora of drugs on the market today, it is challenging for physicians to keep abreast of the information about existing medications. As such, there is a need for physicians to frequently consult drug information (DI) sources, which in itself is not an easy task because of the wide range of DI sources available and frequent discrepancies in DI provided by different sources [6][7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Identification and physicians’ views of their commonly-used drug information sources in Singapore

Lua

Sklar

2011

Int J Clin Pharm

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Most physicians in Singapore search for general drug information using reference texts and consider them to be comprehensive and reliable. Questions pertaining to adverse drug reactions were the drug-related questions physicians most frequently receive. It is important for physicians to have appropriate drug information references and learn methods with which to verify the credibility of drug information obtained from the Internet. Pharmacists can also work to improve their role as providers of drug information.

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Section: Introductionmentioning

confidence: 99%

Identification and physicians’ views of their commonly-used drug information sources in Singapore

Lua

Sklar

2011

Int J Clin Pharm

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“…The co-ordinate files of drugs (ligands) provided in DDPC can be downloaded to create ligand libraries for virtual screening or docking to identify lead compounds, and also for drug interaction and metabolism studies. DDPC also contains links to other rich drug knowledgebases such as RxList (http://www.rxlist.com/script/main/hp.asp) (32), KEGG drug (http://www.genome.jp/kegg/drug/) (8), KEGG compound (http://www.genome.jp/kegg/compound/) (8), PubChem compound (http://www.ncbi.nlm.nih.gov/pccompound) (33), PubChem substance (http://www.ncbi.nlm.nih.gov/pcsubstance) (33) and PharmGKB (http://www.pharmgkb.org/) (34). …”

Section: Utility and Discussionmentioning

confidence: 99%

DDPC: Dragon Database of Genes associated with Prostate Cancer

Maqungo

Kaur

Kwofie

et al. 2010

Nucleic Acids Research

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Prostate cancer (PC) is one of the most commonly diagnosed cancers in men. PC is relatively difficult to diagnose due to a lack of clear early symptoms. Extensive research of PC has led to the availability of a large amount of data on PC. Several hundred genes are implicated in different stages of PC, which may help in developing diagnostic methods or even cures. In spite of this accumulated information, effective diagnostics and treatments remain evasive. We have developed Dragon Database of Genes associated with Prostate Cancer (DDPC) as an integrated knowledgebase of genes experimentally verified as implicated in PC. DDPC is distinctive from other databases in that (i) it provides pre-compiled biomedical text-mining information on PC, which otherwise require tedious computational analyses, (ii) it integrates data on molecular interactions, pathways, gene ontologies, gene regulation at molecular level, predicted transcription factor binding sites on promoters of PC implicated genes and transcription factors that correspond to these binding sites and (iii) it contains DrugBank data on drugs associated with PC. We believe this resource will serve as a source of useful information for research on PC. DDPC is freely accessible for academic and non-profit users via http://apps.sanbi.ac.za/ddpc/ and http://cbrc.kaust.edu.sa/ddpc/.

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“…In particular, two types of electronic drug databases have started to emerge over the past five years: 1) clinically oriented drug databases and 2) chemically oriented drug databases. Examples of some of the better-known clinically oriented drug databases include DailyMed [27] and RxList [28]. These resources typically offer very detailed clinical information (i.e.…”

Section: Databases For Chemical Bioinformaticsmentioning

confidence: 99%

Chapter 3: Small Molecules and Disease

Wishart

2012

PLoS Comput Biol

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“Big” molecules such as proteins and genes still continue to capture the imagination of most biologists, biochemists and bioinformaticians. “Small” molecules, on the other hand, are the molecules that most biologists, biochemists and bioinformaticians prefer to ignore. However, it is becoming increasingly apparent that small molecules such as amino acids, lipids and sugars play a far more important role in all aspects of disease etiology and disease treatment than we realized. This particular chapter focuses on an emerging field of bioinformatics called “chemical bioinformatics” – a discipline that has evolved to help address the blended chemical and molecular biological needs of toxicogenomics, pharmacogenomics, metabolomics and systems biology. In the following pages we will cover several topics related to chemical bioinformatics. First, a brief overview of some of the most important or useful chemical bioinformatic resources will be given. Second, a more detailed overview will be given on those particular resources that allow researchers to connect small molecules to diseases. This section will focus on describing a number of recently developed databases or knowledgebases that explicitly relate small molecules – either as the treatment, symptom or cause – to disease. Finally a short discussion will be provided on newly emerging software tools that exploit these databases as a means to discover new biomarkers or even new treatments for disease.

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Quality of consumer drug information provided by four Web sites

Cited by 28 publications

References 0 publications

Identification and physicians’ views of their commonly-used drug information sources in Singapore

Identification and physicians’ views of their commonly-used drug information sources in Singapore

DDPC: Dragon Database of Genes associated with Prostate Cancer

Chapter 3: Small Molecules and Disease

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