Quality of life after hip fracture in the elderly: A systematic literature review

Peeters, Charles M M; Visser, Eva; Ree, Cornelis L. P. van de; Gosens, Taco; Oudsten, Brenda L. Den; Vries, Jolanda De

doi:10.1016/j.injury.2016.04.018

Cited by 272 publications

(234 citation statements)

References 83 publications

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“…In addition, a study applying both instruments in the generation of QALYs for economic evaluation of an integrated care model for frail elderly found that the intervention was more likely to be considered cost effective with use of the ICECAP-O than the EQ-5D-3 L, indicating the instrument may be more suitable for assessing impact of interventions where the focus is on social and psychological wellbeing [39]. Others have called for the use of multiple instruments in evaluations of interventions for older people, measuring both health-related quality of life as well as broader aspects of quality of life and wellbeing [15, 16]. …”

Section: Discussionmentioning

confidence: 99%

“…Taking the most widely used of these instruments, the EQ-5D focuses upon five dimensions which are highly influenced by physical health and disability but which may not be sensitive to changes in other aspects of wellbeing and quality of life that are important to older people more broadly [13–15] and that are known to be reduced in addition to physical health domains following a hip fracture [16]. Therefore, investigation of instruments which measure quality of life more broadly in these social and emotional functioning domains is warranted in the hip fracture population.…”

Section: Introductionmentioning

confidence: 99%

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Quality of life in older adults following a hip fracture: an empirical comparison of the ICECAP-O and the EQ-5D-3 L instruments

Milte

Crotty

Miller

et al. 2018

Health Qual Life Outcomes

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BackgroundThe purpose of this study was to empirically compare the performance of two generic preference based quality of life instruments, EQ-5D-3 L (with a health and physical function focus) and ICECAP-O (with a wellbeing and capability focus), in a population of older Australians following hip fracture.MethodsOlder adults or their family member proxies (in cases of severe cognitive impairment) following surgery to repair a fractured hip were invited to take part in this cross sectional study. Inclusion criteria included an age of 60 years or older, confirmed falls-related hip fracture and those receiving current palliative care or consented to other research studies were excluded. 87 participants completed the ICECAP-O and EQ-5D-3 L instruments between one and three weeks post-surgery.ResultsFor the hip fracture population, the mean ICECAP-O score was 0.639 (SD 0.206, n = 82) and the mean EQ-5D-3 L utility score was 0.545 (SD 0.251, n = 87). There was a statistically significant positive correlation between the ICECAP-O and EQ-5D-3 L scores (r = 0.529, p = < 0.001).ConclusionsStudy findings indicate significant impairments in quality of life post hip fracture. In multiple regression analyses, age and health-related QoL (measured by the EQ-5D) were significant determinants of ICECAP-O scores, while proxy respondent status, age, and capability-related QoL (measured by the ICECAP-O) were significant determinants of EQ-5D scores. Approaches to measuring and valuing quality of life in this sample, should consider the target domains of the intervention in their choice of instrument. Studies aiming to measure the impact of interventions targeting broader domains of wellbeing and QoL should consider including a broader measure of QoL in conjunction with a HRQoL measure.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Quality of life in older adults following a hip fracture: an empirical comparison of the ICECAP-O and the EQ-5D-3 L instruments

Milte

Crotty

Miller

et al. 2018

Health Qual Life Outcomes

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“…(22)(23)(24) The impact of hip fractures on physical functioning is substantial. (26) Only about one-third to one-half of hip fracture survivors regain prior ambulatory function, (27)(28)(29) and around 13% may be unable to ambulate at all. (26) Only about one-third to one-half of hip fracture survivors regain prior ambulatory function, (27)(28)(29) and around 13% may be unable to ambulate at all.…”

Section: Fundamental Recommendations and Rationalesmentioning

confidence: 99%

Secondary Fracture Prevention: Consensus Clinical Recommendations from a Multistakeholder Coalition

Conley

Adib²,

Adler

et al. 2019

Journal of Bone and Mineral Research

171

111

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Osteoporosis‐related fractures are undertreated, due in part to misinformation about recommended approaches to patient care and discrepancies among treatment guidelines. To help bridge this gap and improve patient outcomes, the American Society for Bone and Mineral Research assembled a multistakeholder coalition to develop clinical recommendations for the optimal prevention of secondary fracture among people aged 65 years and older with a hip or vertebral fracture. The coalition developed 13 recommendations (7 primary and 6 secondary) strongly supported by the empirical literature. The coalition recommends increased communication with patients regarding fracture risk, mortality and morbidity outcomes, and fracture risk reduction. Risk assessment (including fall history) should occur at regular intervals with referral to physical and/or occupational therapy as appropriate. Oral, intravenous, and subcutaneous pharmacotherapies are efficacious and can reduce risk of future fracture. Patients need education, however, about the benefits and risks of both treatment and not receiving treatment. Oral bisphosphonates alendronate and risedronate are first‐line options and are generally well tolerated; otherwise, intravenous zoledronic acid and subcutaneous denosumab can be considered. Anabolic agents are expensive but may be beneficial for selected patients at high risk. Optimal duration of pharmacotherapy is unknown but because the risk for second fractures is highest in the early post‐fracture period, prompt treatment is recommended. Adequate dietary or supplemental vitamin D and calcium intake should be assured. Individuals being treated for osteoporosis should be reevaluated for fracture risk routinely, including via patient education about osteoporosis and fractures and monitoring for adverse treatment effects. Patients should be strongly encouraged to avoid tobacco, consume alcohol in moderation at most, and engage in regular exercise and fall prevention strategies. Finally, referral to endocrinologists or other osteoporosis specialists may be warranted for individuals who experience repeated fracture or bone loss and those with complicating comorbidities (eg, hyperparathyroidism, chronic kidney disease). © 2019 American Society for Bone and Mineral Research.

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“…Hip fracture is a growing public health problem in many parts of the world because of the aging of the global population. Recovery after hip fracture is slow and often complicated by morbidities and disabilities arising from the fracture and subsequent surgery, and individuals experience a decrease in function and health‐related quality of life (HRQoL) . Many factors that have been found to influence recovery after hip fracture surgery are not modifiable, such as older age, poor physical status, and multiple comorbidities.…”

mentioning

confidence: 99%

Preoperative Anemia, Functional Outcomes, and Quality of Life After Hip Fracture Surgery

Sim

Seng

et al. 2018

J American Geriatrics Society

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Quality of life after hip fracture in the elderly: A systematic literature review

Cited by 272 publications

References 83 publications

Quality of life in older adults following a hip fracture: an empirical comparison of the ICECAP-O and the EQ-5D-3 L instruments

Quality of life in older adults following a hip fracture: an empirical comparison of the ICECAP-O and the EQ-5D-3 L instruments

Secondary Fracture Prevention: Consensus Clinical Recommendations from a Multistakeholder Coalition

Preoperative Anemia, Functional Outcomes, and Quality of Life After Hip Fracture Surgery

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