Quality of life and cost of illness in patients with psoriasis in Malaysia: a multicenter study

Tang, Min; Chang, Choong Chor; Chan, Lee Chin; Heng, Agnes

doi:10.1111/j.1365-4632.2011.05340.x

Cited by 45 publications

(65 citation statements)

References 23 publications

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“…While Anti-Tumor Necrosis Factor (Anti-TNF) therapy is associated with improvement in both physical and mental status in psoriasis patients, the role of this treatment on mental health is not known yet (13,14). Many studies have shown that psoriasis negatively impacts the quality of life and its co-morbid conditions (15)(16)(17)(18)(19)(20). However, our findings have not confirmed these results.…”

Section: Discussioncontrasting

confidence: 57%

Evaluation of Some Psychological Factors in Psoriatic Patients

Fakour

Nourmohammadpour

Gholamali

et al. 2015

European Psychiatry

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BackgroundPsoriasis is a disease which may have direct impact on the psychological and social aspects, particularly due to its visibility. To date, we are unaware of any study showing relationship between psoriasis and psychological parameters such as psychological vulnerability and coping strategies.Objectiveto evaluate the effects of psoriasis on some psychological parameters in an Iranian population.MethodsPatients having histopathologically confirmed psoriasis for at least 6 months attending the Clinic of Razi Hospital and evaluated by PASI,CISS,IPQ-RResultsThere were 101 females and 99 males with the mean age of 43.2 (±16.32). The mean PASI Score was 6.58 ± 6.04. Diffuse skin involvement was the commonest form of disease (133 patients, 66.5%). the highest score for Illness perception belongs to those with genitalia involvement (185.2, worst illness perception) and the lowest score for Illness perception belong to those with nail involvement (168.2). Consistently, the lowest score of facing with the problems (CISS: approach strategy to disease) belongs to those with hand involvement (50.5) whereas the highest score belongs to those with genitalia involvement (60.4). There was significant correlation between psychological vulnerability vs. Illness perception score as well as psychological vulnerability vs. coping strategies score. Surprisingly, PASI score had insignificant relationship with illness perception, coping strategies or psychological vulnerability score.ConclusionPASI score as a representing factor of skin involvement has limited role in predicting effect of psoriasis on mental status and illness perception of psoriatic patients. Psychological vulnerability of patients is the main predicting factor of illness perception and coping strategiesThere were 101 females and 99 males with the mean age of 43.2 (±16.32). The mean PASI Score was 6.58 ± 6.04. Diffuse skin involvement was the commonest form of disease (133 patients, 66.5%). the highest score for Illness perception belongs to those with genitalia involvement (185.2, worst illness perception) and the lowest score for Illness perception belong to those with nail involvement (168.2). Consistently, the lowest score of facing with the problems (CISS: approach strategy to disease) belongs to those with hand involvement (50.5) whereas the highest score belongs to those with genitalia involvement (60.4). There was significant correlation between psychological vulnerability vs. Illness perception score as well as psychological vulnerability vs. coping strategies score. Surprisingly, PASI score had insignificant relationship with illness perception, coping strategies or psychological vulnerability score.There were 101 females and 99 males with the mean age of 43.2 (±16.32). The mean PASI Score was 6.58 ± 6.04. Diffuse skin involvement was the commonest form of disease (133 patients, 66.5%). the highest score for Illness perception belongs to those with genitalia involvement (185.2, worst illness perception) and the lowest score for Illness perception belong...

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Section: Discussioncontrasting

confidence: 57%

Evaluation of Some Psychological Factors in Psoriatic Patients

Fakour

Nourmohammadpour

Gholamali

et al. 2015

European Psychiatry

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“…347 Therefore, we performed a literature search for COI studies 348 for the period from January 2010 to December 2013 using 349 the same search terms and databases as Raho et al [9].Our 350 search identified a further nine publications [28][29][30][31][32][33][34][35][36], seven 351 of which involved psoriasis patients with biological treat-352 ment. In the COI analyses conducted by Fonia et al (UK) 353 [28] and Driessen et al (the Netherlands) [29] all patients 354 were treated with biological drugs.…”

mentioning

confidence: 99%

Cost-of-illness in patients with moderate to severe psoriasis: a cross-sectional survey in Hungarian dermatological centres

et al. 2014

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10 Background Despite the widespread availability of bio-11 logical drugs in psoriasis, there is a shortage of disease 12 burden studies. 13 Objectives To assess the cost-of-illness and quality of 14 life of patients with moderate to severe psoriasis in 15 Hungary. 16 Methods Consecutive patients with Psoriasis Area and 17 Severity Index (PASI) [ 10 and Dermatology Life Quality 18 Index (DLQI) [ 10, or treated with traditional systemic 19 (TST) or biological systemic treatment (BST) were inclu-20 ded. Demographic data, clinical characteristics, psoriasis 21 related medication, health care utilizations and employ-22 ment status in the previous 12 months were recorded. 23 Costing was performed from the societal perspective 24 applying the human capital approach. Quality of life was 25 assessed using DLQI and EQ-5D measures. 26 Results Two-hundred patients were involved (females 27 32 %) with a mean age of 51 (SD 13) years, 103 (52 %) 28 patients were on BST. Mean PASI, DLQI and EQ-5D 29 scores were 8 (SD 10), 6 (SD 7) and 0.69 (SD 0.3), 30 respectively. The mean total cost was €9,254/patient/year 31 (SD 8,502) with direct costs accounting for 86 %. The 32 main cost driver was BST (mean €7,339/patient/year).

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“…В некоторых случаях этому способствует про-водимая терапия (ПУВА, цитостатическая). В боль-шинстве исследований, проведенных в разных стра-нах [22][23][24][25]30], отмечено преобладание мужчин среди пациентов с псориазом, за исключением дан-ных, представленных малайскими и турецкими ис-следователями, отметившими небольшое преобла-дание женщин [24,26]. Чаще всего псориаз дебюти-ровал на третьем десятилетии жизни, у женщин не-сколько раньше, чем у мужчин [22,25,26].…”

Section: Discussionunclassified

“…В отличие от других на-блюдений [1,6,8], в данном исследовании было по-казано, что масса тела малайзийских пациентов не влияла на тяжесть течения псориаза. Затраты на ле-чение (исключая затраты на госпитализацию) со-ставляли в среднем 1307,47 ринггит (денежных еди-ниц Малайзии) на человека, при этом отмечалось, что пациенты тратят значительные суммы на неуч-тенные лекарственные средства, которые приобре-таются без рецепта [23]. В штате Малайзии Саравак с декабря 2007 г. по июнь 2009 г. проведены исследо-вания данных 138 пациентов с псориазом.…”

Section: ключевые слова: псориаз заболеваемость распространенностьunclassified