Background: Diabetes mellitus is a chronic disease that cannot be cured entirely, which greatly affects the quality of life. People with diabetes mellitus will experience a negative impact on the quality of life. This is because the patient experiences changes in his life. Measuring the quality of life in diabetic patients is very important, considering that diabetes mellitus sufferers are increasing every year. The purpose of this study was to analyze the factors that affect the quality of life in patients with type 2 DM. Subjects and Method: This was a crosssectional study conducted at Dr. Moewardi Hospital, Central Java, from February to March 2020. A sample of 120 patients with type 2 DM aged >18 years were selected by simple random sampling. The dependent variable was the quality of life. The independent variables were self-care, family support, peer support, length of disease, body mass index, and education. The data were collected by questionnaire and data analysis using path analysis with Stata 13 was used to collect data. Results: Good quality of life in patient with type 2 DM improved with good self-care (b= 2.66; 95% CI= 0.38 to 4.94; p = 0.022), strong family support (b= 3.07; 95% CI= 1.09 to 5.05; p= 0.002), strong peer support (b= 3.43; 95% CI= 1.14 to 5.72; p= 0.003), time period of diagnosis time <6 years (b= -2.90; 95% CI= -5.00 to -0.78; p= 0.007), normal body mass index (b= -2.53; 95% CI= -4.57 to -0.50; p= 0.014), and education ≥senior high school (b= 2.46; 95% CI= 0.72 to 4.21; p= 0.006).
Conclusion:Good quality of life in patients with type 2 DM increases with good self-care, strong family support, strong peer support, time period of diagnosis <6 years, normal body mass index, and education level ≥ senior high school.