Quality of life assessment through the EORTC questionnaires of locally advanced rectal cancer patients treated with preoperative chemo-radiotherapy

Urdániz, Juan Ignacio Arrarás; Vega, F. Arias de la; García, Ruth Vera; Burgaleta, A. Manterola; Aguillo, Maite Martinez; Iturre, E. Villafranca; Pascual, Esteban Salgado

doi:10.1007/s12094-006-0196-4

Cited by 14 publications

(3 citation statements)

References 22 publications

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“…Statistically significant differences existed in numerous dimensions in groups divided by the KPS score (e.g ., stool frequency, P = 0.017). Due to the impact of disease or treatment, sexual function in patients was significantly inhibited, similar to the findings in previous reports by other groups[5,6,24]. The studies by Song et al[25] and Peng et al[26] revealed that treatment of CRC may lead to impotence.…”

Section: Discussionsupporting

confidence: 84%

“…Our data mainly showed lower Cronbach’s α coefficients than those in a similar study by Nowak et al[8], particularly in the urinary frequency dimension (0.363-0.608). Of note, in the studies by Arraras et al[5], Nowak et al[8] and Arraras Urdaniz et al[24], Cronbach’s α coefficients below 0.7 were also obtained for the abdominal pain and blood and mucus in the stool dimensions. The differences between our findings and those of previous studies may be due to differences in the perceptions of quality of life in patients from different regions; however, the differences were still in the acceptable range.…”

Section: Discussionmentioning

confidence: 98%

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Validation of the chinese version of the EORTC QLQ-CR29 in patients with colorectal cancer

Lin¹,

Zhang²,

Wu³

et al. 2017

WJG

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AIMTo assess the validity and reliability of the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Colorectal Cancer 29 (EORTC QLQ-CR29) in Chinese patients with colorectal cancer (CRC).METHODSFrom March 2014 to January 2015, 356 patients with CRC from four different hospitals in China were enrolled in the study, and all patients self-administered the EORTC QLQ-CR29 and the quality of life core questionnaire (EORTC QLQ-C30). Evaluation of the scores was based on the Karnofsky Performance Scale (KPS). The reliability and validity of the questionnaires were assessed by Cronbach’s α coefficient, the Spearman correlation test and Wilcoxon rank sum test.RESULTSThe EORTC QLQ-CR29 showed satisfactory reliability (α > 0.7), although the urinary frequency and blood and mucus in stool dimensions had only moderate reliability (α = 0.608). The multitrait scaling analyses showed good convergent (r > 0.4) and discriminant validity. Significant differences were obtained for each item in the different KPS subgroups (KPS ≤ 80; KPS > 80). Body image and most single-item dimensions showed statistically significant differences in patients with a stoma compared with the rest of the patients.CONCLUSIONThe EORTC QLQ-CR29 exhibits high validity and reliability in Chinese patients with CRC, and can therefore be recommended as a valuable tool for the assessment of quality of life in these patients.

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Section: Discussionsupporting

confidence: 84%

Section: Discussionmentioning

confidence: 98%

Validation of the chinese version of the EORTC QLQ-CR29 in patients with colorectal cancer

Lin¹,

Zhang²,

Wu³

et al. 2017

WJG

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“…In addition to the validation studies, some studies have used EORTC QLQ-CR38 for prospective follow-up. The same scales as in the validation studies as well as the scales addressing male sexual problems, future perspective, weight loss, and chemotherapy side-effects were found to be able to detect relevant differences over time in different treatment groups of patients with colorectal cancer [21-29]. Thus, considerable evidence for the responsiveness to change has been found.…”

Section: Discussionmentioning

confidence: 94%

Validation of the Danish version of the disease specific instrument EORTC QLQ-CR38 to assess Health-related quality of life in patients with colorectal cancer

Thaysen

Jess

Laurberg

et al. 2012

Health Qual Life Outcomes

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BackgroundThe European Organisation for Research and Treatment of Cancer (EORTC) quality of life colorectal questionnaire module (QLQ-CR38) was developed in 1999, and an update, the QLQ CR29 was published recently. To date the Danish version of the questionnaire has not been validated. The aim of this study was to examine the psychometric properties of the Danish version of EORTC QLQ-CR38.MethodsEORTC QLQ-CR38 was administered to 190 patients with colorectal cancer in two Danish hospitals, one month after their operation. A psychometric evaluation of the questionnaire’s structure, reliability, convergent, divergent and known-groups validity was performed.ResultsData from 164 (86.3%) patients were available for analysis. The Danish version of EORTC QLQ-CR38 showed satisfactory psychometric properties for the scales: body image, sexual functioning, male sexual problems and defecations problems. Suboptimal psychometric performances were found for the scales: micturition problems, symptoms of the gastrointestinal tract and weight loss. Evaluation of the psychometric properties of the scale chemotherapy side effects was limited by the low number of patients receiving chemotherapy. It was not possible to assess the psychometric properties of the scale female sexual problems and the single item sexual enjoyment due to a high number of missing values. The homogeneity of the study population made the evaluation of known-group validity difficult.ConclusionsThe results of this study suggest that the validity of the Danish version of EORTC QLQ-CR38 is acceptable. Furthermore, the results support the appropriateness of the updated version, the EORTC QLQ-CR29.

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Quality of Life Issues and Rectal Cancer

Frattini

Marcet

2009

Coloproctology

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Quality of life assessment through the EORTC questionnaires of locally advanced rectal cancer patients treated with preoperative chemo-radiotherapy

Abstract: Quality of life scores and clinical data indicate that the situation of the patients who have received the treatments has been good. Patients under treatment stood it adequately.

Cited by 14 publications

References 22 publications

Validation of the chinese version of the EORTC QLQ-CR29 in patients with colorectal cancer

Validation of the chinese version of the EORTC QLQ-CR29 in patients with colorectal cancer

Validation of the Danish version of the disease specific instrument EORTC QLQ-CR38 to assess Health-related quality of life in patients with colorectal cancer

Quality of Life Issues and Rectal Cancer

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