Quality of life, depression and correlates in HIV+ people at An Hoa Clinic, Ho Chi Minh City

Abstract

With the advance in antiretroviral therapy (ART), improving quality of life (QOL) of people living with HIV/AIDS (PLWH) has become one of the primary goals of clinical practice and research. Understanding factors associated with PLWH's QOL under a country-specific context is critical to be able to achieve this goal. This longitudinal study investigated associations between depression and other factors with QOL among PLWHA at An Hoa Clinic, Ho Chi Minh City, Vietnam. Inclusive criteria were PLWH ≥18 years old, under ART for at least 3 months, and consent to participate in the study. PLWH who were illiterate, too ill, or at the final stage of AIDS were excluded because of their incapacity to self-administer the questionnaire. WHOQOL-BREF-HIV was used to assess QOL. Center for Epidemiologic Studies Depression Scale was used to assess depressive symptoms. Generalized Estimating Equations were used to identify correlates of QOL. The results showed that for every point increased in depression score, QOL score decreased 0.13 points in Physical (p<0.001), 0.12 points in Psychological and Social Relationships (p<0.001), 0.07 points in Level of Independence (p<0.001), 0.09 points in Environment (p<0.001), and 0.15 points in Personal Beliefs domain (p<0.001). PLWH from an economically disadvantaged household had significantly lower QOL scores for all QOL domains but Personal Beliefs with the differences ranging from 0.81 points for Social Relationships to 1.77 points for Environment domain. PLWH with comorbidity (tuberculosis, hepatitis B or C, cardiovascular disease, or kidney diseases) also had significantly lower scores whereas those living with a spouse and adhering to ART medication had significantly higher scores in at least one QOL domain. In conclusion, depressive symptoms, household economy, living with a spouse, having comorbidity and ART medication adherence were important factors associated with PLWH's QOL.

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Efektifitas Aerobik dan Yoga dalam Meningkatkan Kualitas Hidup pada ODHA

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