Quality of life, health status and clinical outcomes in Type 2 diabetes patients

Sundaram, Murali; Kavookjian, Jan; Patrick, Julie Hicks; Miller, Lindsay; Madhavan, Suresh; Scott, Virginia

doi:10.1007/s11136-006-9164-2

Cited by 51 publications

(87 citation statements)

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“…Two other studies reporting β coefficients derived from regression analyses did not find a significant association between depression and hospitalisation rates in patients with diabetes [25,37]. One study reported insufficient information to compute effect sizes [44]. Another study reported a decreased hospital admission rate directly following an emergency department visit [36].…”

Section: Direct Costsmentioning

confidence: 99%

“…In most cases, depression was studied (n=27) [4, 8, 9, 14-16, 18, 20, 21, 23, 25-31, 33, 34, 37, 39-42, 44-46], followed by mental disorders not further specified (n=5) [6,7,9,19,43], anxiety disorders (n=4) [9,14,18,36] and posttraumatic stress disorder (PTSD) (n=3) [14,18,45] (ESM Table 1 [15,31,39,44]. Healthcare costs were examined in various facets in the studies included.…”

Section: Characteristics Of Primary Studiesmentioning

confidence: 99%

“…Inpatient costs were assessed in terms of hospitalisation rates or hospitalisation costs (n=15) [4,6,8,15,20,25,29,31,34,37,39,[42][43][44]46], and length of stay (n=9) [7,15,19,20,25,26,30,42,46]. Outpatient costs were assessed in terms of frequency and costs of outpatient visits (n=19) [4, 6-8, 14, 15, 18-21, 23, 25, 26, 30, 31, 34, 37, 42, 45], mental health specialist visits and costs (n=4) [4,7,8,21,36], emergency department visits (n=11) [4,16,20,21,29,30,34,37,39,42,44] and medication costs (n=6) [4,20,31,34,37,40]. Total healthcare costs or utilisation were studied in 13 primary studies …”

Section: Characteristics Of Primary Studiesmentioning

confidence: 99%

“…Two other studies reporting β coefficients derived from regression analyses did not find a significant association between depression and emergency department visits in depressed patients with diabetes [30,37]. One study did not report sufficient information to compute an effect size [44].…”

Section: Direct Costsmentioning

confidence: 99%

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Healthcare costs in patients with diabetes mellitus and comorbid mental disorders—a systematic review

2010

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Aims/hypothesis We systematically reviewed the impact of comorbid mental disorders on healthcare costs in persons with diabetes. Method We conducted a comprehensive search for studies investigating adult persons (≥18 years old) with diabetes mellitus. All studies that allowed comparison of healthcare costs between diabetic patients with mental disorders and those without were included. Results We identified 4,273 potentially relevant articles from a comprehensive database search. Of these, 31 primary studies (39 publications) fulfilled inclusion criteria, of which 27 examined comorbid depression. Hospitalisation rates and hospitalisation costs, frequency and costs of outpatient visits, emergency department visits, medication costs and total healthcare costs were mainly increased with small to moderate effect sizes in patients with diabetes and comorbid mental disorders compared with diabetic patients without such problems. Frequency (standardised mean difference [SMD]=0.35-1.26) and costs (SMD= 0.33-0.85) of mental health specialist visits were increased in the group with mental health comorbidity. Results regarding diabetes-related preventive services were inconsistent but point to a reduced utilisation rate in diabetic patients with comorbid mental disorders. Statistical heterogeneity between studies was high (I 2 range 64-98%).Pooled overall effects are therefore not reported. Studies included differ substantially regarding sample selection, assessment of diabetes and comorbid mental disorders, as well as in assessment of cost variables. Conclusions/interpretation In light of the increased healthcare costs and inadequate use of preventive services, comorbid mental disorders in patients with diabetes must become a major focus of diabetes healthcare and research.

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Section: Direct Costsmentioning

confidence: 99%

Section: Characteristics Of Primary Studiesmentioning

confidence: 99%

Section: Characteristics Of Primary Studiesmentioning

confidence: 99%

Section: Direct Costsmentioning

confidence: 99%

See 2 more Smart Citations

Healthcare costs in patients with diabetes mellitus and comorbid mental disorders—a systematic review

2010

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“…Patients with T2DM are characterized by high adiposity and reduced fitness, which are also important predictors of Health-related Quality of Life (HRQoL) (2). Despite pharmacological strategies that can modulate many of the factors associated with the disease, T2DM-derived complications are common and have a significant impact in HRQoL, especially with respect to physical function (3) and depression (4).…”

Section: Introductionmentioning

confidence: 99%

The relationship between nutritional status, functional capacity, and health-related quality of life in older adults with type 2 diabetes: A pilot explanatory study

Alfonso-Rosa

Pozo-Cruz

et al. 2013

The Journal of nutrition, health and aging

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Abstract:Objective: To explore the relationship between nutritional status, functional capacity and healthrelated quality of life (HRQoL) in older adults with type 2 diabetes (T2DM). Design: Cross-sectional study. Setting and participants: Forty two non-insulin dependent older adults from a primary care center in Seville, Spain. Measurements: Function was assessed with a battery of standardized physical fitness tests. Nutritional status was assessed using the Mini Nutritional Assessment (MNA) and the European Quality of Life Questionnaire (EQ-5D-3L) was used to assess HRQoL. Results: There was an association between MNAnutritional status and lower body strength as assessed by the chair sit-stand test (rho= .451; p= .037) and between MNA-nutritional status and EQ-5D-3L-HRQoL (EQ-5D-3Lutility, rho= .553; p<.001 and EQ-5D-3LVAS rho= .402; p<.001). An MNA item by item correlation analysis with HRQoL and lower limb strength demonstrated that HRQoL appears to be related to functional capacity (principally lower body strength, motor agility and cardiorespiratory fitness) among participants. These results were maintained when correlations were adjusted for co-morbidity. Conclusion: Our results demonstrated that nutritional status is moderately associated with HRQoL and lower limb strength in patients with T2DM. Our data suggest that more emphasis should be placed on interventions to encourage a correct diet and stress the needed to improve lower body strength to reinforce better mobility in T2DM population

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The association between depression and health‐related quality of life in people with type 2 diabetes: a systematic literature review

Ali

Stone

Skinner

et al. 2010

Diabetes Metabolism Res

165

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The relationships between co-morbid depression in people with diabetes and adverse outcomes including poor HbA(1c) control, adherence to medication and mortality have been examined and confirmed. However, as the awareness of the decrement to health-related quality of life (HRQOL) in people with diabetes and its clinical consequences grows, investigators have become increasingly interested in measuring HRQOL in clinical trials. Given that the psychological factors such as depression may contribute to diminished HRQOL, the present review sought to summarize the association between these variables in people with type 2 diabetes. Articles for a systematic review were obtained via a search performed using MEDLINE, EMBASE and PsycINFO (1980-2007).Fourteen articles fulfilled the inclusion criteria. Studies indicated that self-reported depressive symptoms markedly impaired HRQOL on several domains. However, depression was not related to all sub-domains of HRQOL in all studies, suggesting that the effects of depression on certain aspects of HRQOL may vary between clinical and demographic subgroups. Although a number of shortcomings identified in the current literature should be taken into account for future research, the importance of this review lies in the possibility it raises that the improvements in HRQOL and clinical practice may potentially be achieved by placing greater attention on the identification and management of depression.

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Quality of life, health status and clinical outcomes in Type 2 diabetes patients

Abstract: The fifth author's name was incorrectly coded for abstracting and indexing purposes in the original publication.

Cited by 51 publications

References 0 publications

Healthcare costs in patients with diabetes mellitus and comorbid mental disorders—a systematic review

Healthcare costs in patients with diabetes mellitus and comorbid mental disorders—a systematic review

The relationship between nutritional status, functional capacity, and health-related quality of life in older adults with type 2 diabetes: A pilot explanatory study

The association between depression and health‐related quality of life in people with type 2 diabetes: a systematic literature review

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