BACKGROUND : Quality of life in climacteric women is intrinsically related to signs and symptoms influenced by estrogen decline, in addition to psychosocial factors linked to the natural aging process, in this context this study aims to outline a sociodemographic, clinical and quality of life profile. life of climacteric women servants of the University of the State of Rio Grande do Norte - UERN.METHODS: this is a research with a descriptive, exploratory and quantitative approach . The population consisted of female workers from UERN, aged between 40 and 65 years. The total sample consisted of 64 women who responded to the forms and only one refused to respond.RESULTS: the age range of the participants can be defined, so that 53.97% (n=34) are aged up to 50 years, 55.56% (n=35) are married or in a stable relationship. Regarding ethnicity, whites and browns had the same percentage of 44.44% (n=28). As for the city in which they reside, the largest number of women resides in Mossoró (RN), representing 82.53% (n=52) . The predominance of poor quality of life in the SF-36 was evidenced in the domains referring to pain, general health status and the domain referring to vitality. As for the SF-36 questionnaire, which represents the level of satisfaction with current health, 4.76% (n=3) stated that they fit the level considered excellent, 44.44% (n=28) very good, 46, 03% (n=29) were good and only 4.77% (n=3) represented a satisfaction with their current health considered bad. The intensity of symptoms related to estrogen deficiency, established by the Kupperman menopause index , was classified as: Mild 55.56% ( n° =35), moderate 41.27% ( n° =26) and severe 3.17% ( No. =2) .CONCLUSIONS: the occurrence of symptoms and perception of menopausal symptoms differ from woman to woman, to a greater or lesser extent. From this, it highlights the need for a qualified and individualized listening to the needs of these women in the health services and, in this way, it is possible to develop applicable solutions for solving problems based on the profile of each woman.