Quality of life measurement in gastrointestinal and liver disorders

Mr, Borgaonkar; Ej, Irvine

doi:10.1136/gut.47.3.444

Cited by 185 publications

(158 citation statements)

References 121 publications

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“…Most studies exploring the QoL in CD patients used generic multi-item and multi-dimensional instruments developed for chronic disorders. [24][25][26][27][28] The most widely used generic tools to estimate health-related QoL in CD were the Short Form Health Survey questionnaire 26 and the Psychological General Well-being index. 28 It is only recently that CD-specific questionnaires have been developed for pediatric 29,30 and adult patients 31,32 and translated into other languages.…”

Section: Qolmentioning

confidence: 99%

Psychological morbidity of celiac disease: A review of the literature

et al. 2015

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Section: Qolmentioning

confidence: 99%

Psychological morbidity of celiac disease: A review of the literature

et al. 2015

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“…QOL has been evaluated in a large number of chronic medical and gastrointestinal conditions, such as dyspepsia, inflammatory bowel diseases, liver diseases, etc. [3][4][5][6][7] . Well-developed and validated questionnaires have been used as instruments for QOL measurement.…”

Section: Introductionmentioning

confidence: 99%

“…It is encouraged to use both instruments in clinical research to gain substantial information [5] . Since the development of the first liver-specific questionnaire, the chronic liver disease questionnaire (CLDQ) [7] , the QOL research in chronic liver diseases have been steadily reported [6,[8][9][10][11][12] . Previous studies in Western patients showed that chronic liver disease (CLD) had negative impact on QOL, and QOL worsened as the severity of disease increased [8,9,[12][13][14] .…”

Section: Introductionmentioning

confidence: 99%

Chronic liver disease questionnaire: Translation and validation in Thais

Sobhonslidsuk

Silpakit²,

Kongsakon³

et al. 2004

WJG

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AIM: Quality of life (QOL) is a concept that incorporates many aspects of life beyond "health". The chronic liver disease questionnaire (CLDQ) was developed to evaluate the impact of chronic liver diseases (CLD) on QOL. The objectives of this study were to translate and validate a liver specific questionnaire, the CLDQ. METHODS:The CLDQ was formally translated from the original version to Thai language with permission. The translation process included forward translation, back translation, cross-cultural adaptation and a pretest. Reliability and validity of the translated version was examined in CLD patients. Enrolled subjects included CLD and normal subjects with age-and sex-matched. Collected data were demography, physical findings and biochemical tests. All subjects were asked to complete the translated versions of CLDQ and SF-36, which was previously validated. Cronbach's alpha and test-retest were performed for reliability analysis. One-way Anova or non-parametric method was used to determine discriminant validity. Spearman's rank correlation was used to assess convergent validity. P -value <0.05 was considered statistically significant. RESULTS:A total of 200 subjects were recruited into the study, with 150 CLD and 50 normal subjects. Mean ages (SD) were 47.3(11.7) and 49.1(8.5) years, respectively. The number of chronic hepatitis: cirrhosis was 76:74, and the ratio of cirrhotic patients classified as Child A:B:C was 37 (50%): 26(35%): 11(15%). Cronbach's alpha of the overall CLDQ scores was 0.96 and of all domains were higher than 0.93. Item-total correlation was >0.45. Test-retest reliability done at 1 to 4 wk apart was 0.88 for the average CLDQ score and from 0.68 to 0.90 for domain scores. The CLDQ was found to have discriminant validity. The highest scores of CLDQ domains were in the normal group, scores were lower in the compensated group and lowest in the decompensated group. The significant correlation between domains of the CLDQ and SF-36 was found. The average CLDQ score was strongly correlated with the general health domain of . CONCLUSION:The translated CLDQ is valid and applicable in Thais with CLD. CLDQ reveals that QOL in these patients is lower than that in normal population. QOL is more impaired in advanced stage of CLD.Sobhonslidsuk A, Silpakit C, Kongsakon R, Satitpornkul P, Sripetch C. Chronic liver disease questionnaire: Translation and validation in Thais.

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“…Moreover, using arbitrary endpoints renders comparisons between different studies impossible. More recently, investigators turned to the established and authorized questionnaires for comparisons between gastric surgery procedures [10-15, 18, 20], because there are several combinations of core questionnaires and disease-specific modules that are considered appropriate and have been approved for evaluation of QOL [23,24]. A combination of SF-36, a core questionnaire, and GSRS, a symptom-specific QOL, has been one of the examples [11,14], but the GSRS may have a tendency to overlook some of the symptoms that are peculiar to the patients who have undergone gastrectomy and are unusual for other disorders of the gastrointestinal tract.…”

Section: Discussionmentioning

confidence: 99%

Characteristics and clinical relevance of postgastrectomy syndrome assessment scale (PGSAS)-45: newly developed integrated questionnaires for assessment of living status and quality of life in postgastrectomy patients

et al. 2014

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Background Lack of a suitable instrument to comprehensively assess symptoms, living status, and quality of life in postgastrectomy patients prompted the authors to develop postgastrectomy syndrome assessment scale (PGSAS)-45. Methods PGSAS-45 consists of 45 items in total: 8 items from SF-8, 15 items from GSRS, and an additional 22 items selected by 47 gastric surgeons. Using the PGSAS-45, a multi-institutional survey was conducted to determine the prevalence of postgastrectomy syndrome and its impact on everyday life among patients who underwent various types of gastrectomy. Eligible data were obtained from 2,368 patients operated and followed at 52 institutions in Japan. Of these, data from 1,777 patients were used in the current study in which symptom subscales of the PGSAS-45 were determined. We also considered the characteristics of the postgastrectomy syndrome and to what extent these symptoms influence patients' living status and quality of life (QOL).Results By factor analysis, 23 symptom-related items of PGSAS-45 were successfully clustered into seven symptom subscales that represent esophageal reflux, abdominal pain, meal-related distress, indigestion, diarrhea, constipation, and dumping. These seven symptom subscales and two other subscales measuring quality of ingestion and dissatisfaction for daily life, respectively, had good internal consistency in terms of Cronbach 0 s a (0.65-0.88).

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Quality of life measurement in gastrointestinal and liver disorders

Cited by 185 publications

References 121 publications

Psychological morbidity of celiac disease: A review of the literature

Psychological morbidity of celiac disease: A review of the literature

Chronic liver disease questionnaire: Translation and validation in Thais

Characteristics and clinical relevance of postgastrectomy syndrome assessment scale (PGSAS)-45: newly developed integrated questionnaires for assessment of living status and quality of life in postgastrectomy patients

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