Quality of life of elderly patients with isolated systolic hypertension

Fletcher, Astrid; Bulpitt, C J; Tuomilehto, Jaakko; Browne, John; Bossini, A; Kawecka−Jaszcz, Kalina; Kivinen, Paula; O’Brien, Eoin; Staessen, Jan A.; Thijs, Lutgarde; Vänskä, O; Vanhanen, Hannu

doi:10.1097/00004872-199816080-00006

Cited by 23 publications

(4 citation statements)

References 17 publications

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“…In the general population QOL decreases with advancing age and varies greatly between socioeconomic and disease groups (e.g., angina pectoris, congestive heart failure, diabetes, asthma, femoral neck fractures, low back pain) [2,9,10,[27][28][29][30][31]. In the present study we have simultaneously considered the majority of most important chronic diseases and health conditions.…”

Section: Discussionmentioning

confidence: 99%

“…In several studies, the clear-cut relationship has been shown between the hypertension as well as other diseases of cardiovascular system and QOL [2,9,10,32,33]. However, little attention have been given to the focus on the relative contribution of hospitalisation and CVD in determination of QOL.…”

Section: Discussionmentioning

confidence: 99%

“…Many health conditions can influence the subjective assessment of QOL of the seniors, among them CVD is considered to play a key role [8][9][10]. In addition to co-existing diseases, the social status, nutritional state and functional efficiency can determine the subjective assessment of QOL and state of health as well.…”

Section: Introductionmentioning

confidence: 99%

“…Studies assessing QOL in CVD have usually concentrated either on cross-sectional correlations in different groups of older subjects [6,9,14], or follow-up after CVD events [2,10,15]. In both types of studies it is difficult to distinguish between the influence of CVD per se and the impact of other existing conditions.…”

Section: Introductionmentioning

confidence: 99%

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Influence of chronic cardiovascular disease and hospitalisation due to this disease on quality of life of community-dwelling elderly

Borowiak

Kostka

2006

Qual Life Res

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The aim of this study was to describe the impact of chronic cardiovascular disease (CVD) and hospitalisation due to this disease on quality-of-life (QOL) in community-dwelling elderly. The study was carried out in the three age- and gender-matched groups of older subjects: 100 elderly without CVD, 100 elderly with CVD and 100 patients actually hospitalised for the cardiologic reasons. The assessment included demographic and social variables, health status, nutritional state, physical activity (PA), physical and cognitive function. QOL was assessed with the Euroqol 5D questionnaire. Presence of CVD per se detracted from QOL only moderately, increasing the subjective perception of pain/discomfort. Hospitalisation was connected with the reduction of the majority of QOL dimensions and the decrease of rating on visual analogue scale (VAS). When taking into account all confounders the presence of CVD did not significantly contribute to overall QOL, while hospitalisation decreased the usual activity dimension of QOL and VAS, but interestingly, improved the perception of well-being in relation to anxiety/depression. Variables that most powerfully detracted from QOL were lower functional status, higher number of medications used, poor nutritional state, low habitual PA and above all, depression. These findings suggest that physical and cognitive function as well as regular PA may affect QOL more in community-dwelling elderly than the presence of CVD or even need of hospitalisation.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Influence of chronic cardiovascular disease and hospitalisation due to this disease on quality of life of community-dwelling elderly

Borowiak

Kostka

2006

Qual Life Res

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Successful Blood Pressure Control in the African American Study of Kidney Disease and Hypertension

Wright¹

2002

Arch Intern Med

123

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Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia

McGuinness

Todd

Passmore

et al. 2006

Cochrane Database of Systematic Reviews

145

112

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There was no convincing evidence from the trials identified that blood pressure lowering prevents the development of dementia or cognitive impairment in hypertensive patients with no apparent prior cerebrovascular disease. There were significant problems identified with analysing the data, however, due to the number of patients lost to follow-up and the number of placebo patients given active treatment. This introduced bias. More robust results may be obtained by analysing one year data to reduce differential drop-out or by conducting a meta-analysis using individual patient data.

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Quality of life of elderly patients with isolated systolic hypertension

Abstract: At entry to the trial there was considerable heterogeneity of patients in terms of measures of quality of life and cognitive performance. It remains to be determined whether these influence subsequent quality of life during randomized treatment.

Cited by 23 publications

References 17 publications

Influence of chronic cardiovascular disease and hospitalisation due to this disease on quality of life of community-dwelling elderly

Influence of chronic cardiovascular disease and hospitalisation due to this disease on quality of life of community-dwelling elderly

Successful Blood Pressure Control in the African American Study of Kidney Disease and Hypertension

Blood pressure lowering in patients without prior cerebrovascular disease for prevention of cognitive impairment and dementia

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