Quality of life of idiopathic pulmonary fibrosis patients

Impact of angiotensin II type 1 and G-protein-coupled Mas receptor expression on the pulmonary performance of patients with idiopathic pulmonary fibrosis

“…The increase in AT1R is associated with worse lung function, as seen by the decrease in FVC% and FEV 1 %, whereas the opposite association was found with Mas-R. The importance of these results is reinforced by Bárczi et al [ 9 ] who, on studying patients with IPF, found a positive correlation between quality of life and FVC ( r = 0.4, P < 0.05), demonstrating that by improving functional parameters, the patients’ well-being is also improved. Further studies should be conducted to confirm and amplify these important findings.…”

“…Due to the progressive loss of lung function caused by IPF, an individual’s quality of life decreases as the disease progresses [ 9 ]. In addition, due to the large number of associated comorbidities and the need to apply complex resources to manage them, IPF generates a substantial burden on health services [ 10 , 11 ].…”