Quantification in comprehensive two-dimensional gas chromatography and a model of quantification based on selected summed modulated peaks

Organic Compound in Airborne Particles and their Genottoxic Effects in Mexico City

“…Thermal desorption aerosol (TAG) was developed for in-situ identification of organic aerosols (William et al, 2006), and a newer version of this system coupled to GCxGC (2D-TAG) was applied for the time-resolved measurement of organic compounds in ambient aerosols (Goldstein et al, 2008), showing extraordinary improved separation capabilities for the OA. Although GCxGC offers a great deal of information at the molecular level, quantitative analysis has been less developed (Amador-Muñoz & Marriott, 2008). In a recent paper, we proposed a simple method based on isotope-dilution mass spectrometry to quantify PAH on aerosol samples employing a reference material of urban dust (NIST SRM1649a).…”

Theory and Practice of UHPLC and UHPLC–MS

“…Advanced data analysis techniques, e.g., multivariate data analysis, can also be applied to LC Â LC data, despite it being more complicated with respect to 1D-LC separations (Pierce and Mohler, 2012;Bailey and Rutan, 2013).…”

“…Citrus species, particularly orange, are commonly regarded as the most complex natural source of these compounds. Some of these compounds are reported to show different functional properties, such as antioxidant activity (Beutner et al, 2001;Leach et al, 1998), prevention of cancer (Nishino et al, 1999), cardiovascular diseases (Arab and Steck, 2000;Rao and Rao, 2007), and macular degeneration (Snodderly, 1995). Carotenoids are a very complex group of compounds based on a C40-tetraterpenoid skeleton and are usually classified into two main groups: hydrocarbon carotenoids, known as carotenes (e.g., b-carotene and lycopene), and oxygenated carotenoids, known as xanthophylls (e.g., b-cryptoxanthin and lutein).…”

Development of a Combined Heart-Cut and Comprehensive Two-Dimensional Gas Chromatography System to Extend the Carbon Range of Volatile Organic Compounds Analysis in a Single Instrument

“…Our previous measurement approach, detailed in Dunmore et al (2015), used comprehensive two-dimensional GC (GC×GC) [3], a method that can increase the number of VOC species identified in complex mixtures, such as urban air, when compared to single column GC [4]. GC×GC instruments subject the entire sample under analysis to a separation in two dimensions through the use of two GC columns connected via a modulator.…”