Flexible, surface-active, polystyrene-based, optically transparent films, embedded with a coating of commercially sourced titanium dioxide nanoparticles (Evonik P25), are made by coupling the protonated TiO2 particles with an anionic phase transfer agent (tetraphenylborate), to create an ion paired species that is drawn to a water/dichloromethane (DCM) interface to form a monolayer. The latter is subsequently embedded in a thin polystyrene (PS) film, typically 2.5 m thick, by allowing the DCM to evaporate. The resulting clear TiO2 Surface-Exposed Nanoparticle (TiO2-SEN) thin plastic films are characterised using scanning electron microscopy (SEM) and found to have 25.3 ± 5.4 nm nanoparticles exposed to the air on one side and PS on the other. The photocatalytic activity of these films is demonstrated using a number of different tests including: the photooxidation of 4-chlorophenol (4-CP) and methylene blue (MB) and the photoreduction of resazurin (Rz) and MB. In most of these tests the photoactivity of the film is more than double compared against that of a commercial photocatalytic film, Activ TM .