Quantification of noninvasive fat reduction: A systematic review

Auh, Sogyong; Iyengar, Sanjana; Weil, Alexandra; Bolotin, Diana; Cartee, Todd V.; Dover, Jeffrey S.; Maher, Ian A.; Sobanko, Joseph F.; Cohen, Joel L.; Poon, Emily; Alam, Murad

doi:10.1002/lsm.22761

Cited by 16 publications

(18 citation statements)

References 49 publications

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“…Furthermore, there were statistically significant differences in favor of the Cryolipolysis group (P < 0.001) regarding the effect of Cryolipolysis on waist-to-hip ratio and subcutaneous fat thickness measured by ultrasonography. Although the accuracy of waist circumference and the waist-to-hip ratio, as well as the ultrasonography in reflecting the percentage of fat reduction was variable and dependent on the evaluator experience, they still were easy, valid, reliable, and accurate tools to measure the thickness of the fat [41]. This positive effect of Cryolipolysis in the current study were assumed to be due to its reshaping and re-contouring effects, which was approved by many studies [19,[41][42][43].…”

Section: Discussionmentioning

confidence: 99%

Systemic Effects of Cryolipolysis in Central Obese Women: A Randomized Controlled Trial

et al. 2020

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Background and Objectives To investigate the adding effect of Cryolipolysis to a low‐calorie diet program on lipid profile, liver enzymes, body mass index, waist‐to‐hip ratio, and volume reduction of subcutaneous fat tissue in central obese women. Study Design/Materials and Methods Sixty central obese women were randomly divided into two equal groups. Women in the control group received prescribed low‐calorie diet regimen only, while women in the study group received three Cryolipolysis sessions plus the same dietary regimen for 3 months. Assessment of women in each group for weight, height to obtain the body mass index, waist‐to‐hip ratio, and abdominal subcutaneous fat thickness as well as evaluation of lipid profile and liver enzymes was done just before starting the treatment procedures and immediately after ending the study duration. Results There were statistically significant improvements of waist‐to‐hip ratio, body mass index, total cholesterol, triglycerides, low‐ and high‐density lipoprotein, as well as liver enzymes in favor of the study group (P < 0.001). Conclusion Women who underwent Cryolipolysis and diet program had better improvement in components of lipid profile and liver enzymes than women who were maintained over diet program alone. Measures to decrease waist circumference, associated with abdominal subcutaneous fat reduction, enhanced the systemic effects of Cryolipolysis. Lasers Surg. Med. © 2020 Wiley Periodicals, Inc.

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Section: Discussionmentioning

confidence: 99%

Systemic Effects of Cryolipolysis in Central Obese Women: A Randomized Controlled Trial

et al. 2020

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“…Accurate quantification of volumetric fat reduction is difficult (9,10). Auh and Alum (11) note that while MRI is the current "gold standard", it is costly and may not be readily available. Two dimensional photographs are commonly used as "proof" of outcome, but patient position, lighting, change in patient weight, Downloaded by [University of California, San Diego] at 09:33 02 April 2016 clothing, and a difference in camera operator personnel are noted confounding variables.…”

Section: Discussion Many Noninvasive Devices Claim Subcutaneous Fat mentioning

confidence: 98%

Quantification of adipose volume reduction with a prospective study analyzing the application of external radiofrequency energy and high voltage ultrashort pulse duration electrical fields

Duncan¹,

Kim

Temaat³

2016

Journal of Cosmetic and Laser Therapy

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To date, there have been no objective measurements of subcutaneous volume loss following treatments with a noninvasive radiofrequency (RF)-based device. Twenty female patients were treated with a suction-coupled bipolar RF device using external RF energy combined with pulsed electromagnetic RF energy for subcutaneous fat reduction. Parameters followed included weight, Vectra measurements of abdominal circumference and torso volume, and high-definition ultrasound measurements of fat thickness. Measurements were taken before treatment and three times following treatment. Analysis of the measured parameters showed that mean circumference reduction of 2.30 cm was noted at three months post-treatment. Independent volumetric analysis showed a mean subcutaneous volume reduction of 428 cc three months following RF treatment. High-resolution ultrasound fat thickness was reduced by a mean of 39.6% three months following the final BodyFX treatment. Independent and paired-sample t-tests showed a p value of < 0.05. Repeated measures of analysis of covariance (ANCOVA) adjusted for differences in age, as well as height and weight (proxy for body mass index) to minimize individual differences and control for extraneous variables that may affect the pre- and post-treatment results were analyzed. No confounding variables were found. All analyses were conducted using IBM SPSS 21.0.

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“…Although ultrasound measures have been used by other studies, limitations like subjectivity of landmarks assignments and dependence on operator experience are highlighted. However, a gold standard method is not yet defined 8 …”

Section: Discussionmentioning

confidence: 99%

“…Data on efficacy and safety of cryolipolysis have become more frequent in the literature, 8 however, the studies include, in general, small sample sizes and different characteristics may be related with an unsuccessful treatment 5 …”

Section: Introductionmentioning

confidence: 99%

“…[1][2]5,6 In Brazil, the National Health Surveillance Agency (ANVISA), responsible for sanitary control of products and services, recognizes the technique and provided authorization for its commercialization. 7 Data on efficacy and safety of cryolipolysis have become more frequent in the literature, 8 however, the studies include, in general, small sample sizes and different characteristics may be related with an unsuccessful treatment. 5 This study aims to analyze the efficacy of cryoplipolysis on visible local fat reduction in submental region, arms, or male breast (pseudogynecomastia) in Brazilian subjects.…”

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confidence: 99%

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Cryolipolysis for local fat reduction in adults from Brazil: A single‐arm intervention study

Gusmão¹,

Canella

Gusmão³

et al. 2020

J of Cosmetic Dermatology

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Background Localized fat is a matter of great concern among individuals from today's society. Cryolipolysis is a noninvasive technique that have shown great results in reducing localized fat. Aims To analyze the efficacy of cryoplipolysis on visible local fat reduction in submental region, arms, or male breast (pseudogynecomastia) in Brazilian subjects, and to assess possible factors associated with treatment success. Methods Single‐arm, nonrandomized trial, with volunteers from both genders with visible excess fat in the arms or submental region or men presenting pseudogynecomastia. Eligible subjects were submitted to physical, photographic, and ultrasound analysis before and three months after intervention. A single cryolipolysis session was performed using specific methods for each region, followed by a local massage for two minutes. Data were described as measures of central tendency and dispersion and measures of frequency. Reduction in measurements and factors associated with treatment success was analyzed using appropriate statistical tests. Results Thirty‐six subjects underwent one session of cryolipolysis in each area (22 subjects treated the arms, 20 the submental region and 9 the breast). In general, a mean reduction of 19.1% was observed. Significant differences were observed for almost all body parts analyzed. Body mass index was the only variable showing a significant relationship with intervention results. Conclusions Cryolipolysis is a useful noninvasive tool in reduction of visible localized fat in arms and submental region and of pseudogynecomastia. Obese subjects are not benefited by the treatment.

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Quantification of noninvasive fat reduction: A systematic review

Cited by 16 publications

References 49 publications

Systemic Effects of Cryolipolysis in Central Obese Women: A Randomized Controlled Trial

Systemic Effects of Cryolipolysis in Central Obese Women: A Randomized Controlled Trial

Quantification of adipose volume reduction with a prospective study analyzing the application of external radiofrequency energy and high voltage ultrashort pulse duration electrical fields

Cryolipolysis for local fat reduction in adults from Brazil: A single‐arm intervention study

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