Quantification of tricuspid regurgitation by Doppler color flow mapping after cardiac transplantation

Mügge, Andreas; Daniel, Werner G.; Herrmann, G.; Simon, R.; Lichtlen, Paul R.

doi:10.1016/0002-9149(90)90378-e

Cited by 70 publications

(17 citation statements)

References 10 publications

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“…Tricuspid regurgitation was identified in the apical four-chamber view as a large color mosaic systolic jet, and jet area (JA) and right atrial (RA) area were then planimetered on the still-frame image of maximal JA. The RI, ratio of JA to RA area expressed as a percentage, was calculated to confirm the presence of severe TR, which was defined as an RI Ͼ33% (17)(18)(19)(20). The diastolic tricuspid annular diameter (TAD) was measured as previously described on a still image of the apical four-chamber view as the maximal distance between the insertion hinge points of the septal and anterior tricuspid leaflets at the time of maximal leaflet excursion in diastole (17,21).…”

Section: Methods and Study Protocolmentioning

confidence: 99%

Does lowering pulmonary arterial pressure eliminate severe functional tricuspid regurgitation?

Sadeghi

Kimura

Raisinghani

et al. 2004

Journal of the American College of Cardiology

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Section: Methods and Study Protocolmentioning

confidence: 99%

Does lowering pulmonary arterial pressure eliminate severe functional tricuspid regurgitation?

Sadeghi

Kimura

Raisinghani

et al. 2004

Journal of the American College of Cardiology

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“…Before surgery, all patients underwent routine echocardiography and cardiac catheterization. The severity of TR was judged by the size of the regurgitant jet on a color flow image [10] using a Toshiba Sonolayer SSH-160A (Tokyo, Japan). Pressure values of each cardiac chamber, cardiac index, and Qp/Qs were obtained by cardiac catheterization.…”

Section: Patient Selectionmentioning

confidence: 99%

Sarcoplasmic reticulum Ca2+ regulatory protein gene expression in human right atrium under hemodynamic overload

et al. 1999

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Sarcoplasmic reticulum (SR) Ca2+-adenosine triphosphatase (ATPase) mRNA expression is reduced in the failing human myocardium. However, it is not known whether SR Ca2+-regulatory protein gene expression is altered in human myocardial tissue subjected to pressure overload or volume overload. We sought to determine whether SR Ca2+-regulatory protein gene expression is altered in human atrial tissue subjected to mechanical overload. We obtained right atrial myocardial tissue (about 250mg) at open-heart surgery from three groups of patients: no hemodynamic overload to the right atrium (control group; 12 patients), atrial septal defect (ASD group; 8 patients), and tricuspid regurgitation (TR group; 7 patients). We measured the myocyte size, the area of interstitial fibrosis, SR Ca2+,-ATPase, and ryanodine receptor mRNA abundance. The isolated cardiocyte area and the percent area of interstitial fibrosis were in the order TR > ASD > control (P < 0.05). The SR Ca2+-ATPase mRNA level in TR was significantly decreased (P = 0.004) compared with the control, whereas in the ASD group it did not differ significantly from control. There were no significant differences in ryanodine receptor mRNA levels among the three groups. SR Ca2+-ATPase gene expression was downregulated in human atrial tissue with TR but not in ASD, which might have resulted from the differences in the degree and/or the type of hemodynamic overload to the myocardium.

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“…In most cases TR is mild and asymptomatic, but some cases of moderate or severe TR are related to morbidity and mortality [1–5]. Doppler echocardiography is the most common technique used for the detection and evaluation of severity of TR [6, 7]. The treatment of severe symptomatic TR is mainly conservative with diuretics.…”

Section: Introductionmentioning

confidence: 99%

Tricuspid Valve Regurgitation after Orthotopic Heart Transplantation: Prevalence and Etiology

Berger

Zahav

Kassif

et al. 2012

Journal of Transplantation

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Background. Tricuspid valve regurgitation (TR) after orthotopic heart transplantation (OHT) is common. The aims of this study were to determine the prevalence of TR after OHT, to examine the correlation between its development and various variables, and to determine its outcomes. Methods. All 163 OHT patients who were followed up between 1988 and 2009 for a minimal period of 12 months were divided into those with no TR/mild TR and those with at least mild-moderate TR, as assessed by doppler echocardiography. These groups were compared regarding preoperative hemodynamic variables, surgical technique employed, number of endomyocardial biopsies, number of acute cellular rejections, incidence of graft vasculopathy, and clinical outcomes. Results. At the end of the followup (average 8.2 years) significant TR was evident in 14.1% of the patients. The development of late TR was found by univariate, but not multivariate, analysis to be significantly correlated with the biatrial surgical technique (P < 0.01) and the presence of graft vasculopathy (P < 0.001). TR development was found to be correlated with the need for tricuspid valve surgery but not with an increased mortality. Conclusions. The development of TR after OHT may be related to the biatrial anastomosis technique and to graft vasculopathy.

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Quantification of tricuspid regurgitation by Doppler color flow mapping after cardiac transplantation

Cited by 70 publications

References 10 publications

Does lowering pulmonary arterial pressure eliminate severe functional tricuspid regurgitation?

Does lowering pulmonary arterial pressure eliminate severe functional tricuspid regurgitation?

Sarcoplasmic reticulum Ca2+ regulatory protein gene expression in human right atrium under hemodynamic overload

Tricuspid Valve Regurgitation after Orthotopic Heart Transplantation: Prevalence and Etiology

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