Quantifying and dispensing of magnetic particles in a self-assembled magnetic particle array

Song, Suk‐Heung; Yoon, Jinsik; Jeong, Yongkyo; Jung, Yong Gyun; Abelmann, Léon; Park, Wook

doi:10.1016/j.jmmm.2021.168341

Cited by 4 publications

(4 citation statements)

References 16 publications

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“…We often use our MagOD system with a suspension of magnetic micro-and nanoparticles. This works particularly well for magnetic needles 50 and magnetic disks. 51 In principle, spherical particles should not show a change in transmission under rotation of an external field.…”

Section: Suspensions Of Magnetic Nanoparticlesmentioning

confidence: 82%

An open-source automated magnetic optical density meter for analysis of suspensions of magnetic cells and particles

Welleweerd

Hageman

Pichel

et al. 2022

Review of Scientific Instruments

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We present a spectrophotometer (optical density meter) combined with electromagnets dedicated to the analysis of suspensions of magnetotactic bacteria. The instrument can also be applied to suspensions of other magnetic cells and magnetic particles. We have ensured that our system, called MagOD, can be easily reproduced by providing the source of the 3D prints for the housing, electronic designs, circuit board layouts, and microcontroller software. We compare the performance of our system to existing adapted commercial spectrophotometers. In addition, we demonstrate its use by analyzing the absorbance of magnetotactic bacteria as a function of their orientation with respect to the light path and their speed of reorientation after the field has been rotated by 90°. We continuously monitored the development of a culture of magnetotactic bacteria over a period of 5 days and measured the development of their velocity distribution over a period of one hour. Even though this dedicated spectrophotometer is relatively simple to construct and cost-effective, a range of magnetic field-dependent parameters can be extracted from suspensions of magnetotactic bacteria. Therefore, this instrument will help the magnetotactic research community to understand and apply this intriguing micro-organism.

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Section: Suspensions Of Magnetic Nanoparticlesmentioning

confidence: 82%

An open-source automated magnetic optical density meter for analysis of suspensions of magnetic cells and particles

Welleweerd

Hageman

Pichel

et al. 2022

Review of Scientific Instruments

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“…In addition, demands are growing around the world for high-quality, multiplex, and automatic equipment that can accurately identify specific virus strains due to their similarity to other pathogens that have similar symptomatic patterns. [31][32][33][34] Herein, we introduce "VEUS," an innovative and miniaturized allin-one platform designed to autonomously execute antibody immobilization (conjugation), quality control of the immobilized antibody on RSMPs, [35,36] and subsequent their immunoassays, thereby mitigating human errors and elevating experimental reproducibility. The VEUS system leverages chemically treated RSMPs for full automation steps of both antibody immobilization and immunoassays.…”

Section: Introductionmentioning

confidence: 99%

“…Herein, we introduce “VEUS,” an innovative and miniaturized all‐in‐one platform designed to autonomously execute antibody immobilization (conjugation), quality control of the immobilized antibody on RSMPs, [ 35,36 ] and subsequent their immunoassays, thereby mitigating human errors and elevating experimental reproducibility. The VEUS system leverages chemically treated RSMPs for full automation steps of both antibody immobilization and immunoassays.…”

Section: Introductionmentioning

confidence: 99%

All‐in‐one platform: Versatile, Easy, and User‐friendly System (VEUS) based on automated and expert‐independent antibody immobilization and immunoassay by utilizing customized movement of magnetic particles

Yoon,

Kim,

Lim

et al. 2024

Biotechnology Journal

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The ELISA is the most worldwide method for immunoassay. However, the ELISA is losing ground due to low reproducibility of manual experimental processes in both R&D and IVD areas. An automated platform is a good solution, but there are still limitations owning to extremely high cost and requiring large space to set up especially for a small size laboratory. Here, we present a novel all‐in‐one platform called “VEUS” settable on the laboratory table that offers comprehensive automation of the entire multiplex immunoassay process by exploiting antibody conjugated magnetic particles, quality control and then immunoanalytical reaction, thereby enhancing detection sensitivity and high reproducibility. As a proof of concept, the system exhibits a sensitive LOD of 0.6 and 3.1 pg mL−1 within 1 h run, comparable precision that of molecular diagnostic systems based on PCR method, enabling rapid multiplex diagnosis of Influenza A, Influenza B, and COVID‐19 viruses with similar symptoms. Through automation by the all‐in‐one system, it can be used by novice users, something innovative for immunoassays, relying heavily on user experience. Furthermore, it can contribute to streamline entire immunoassay processes of diverse biomarkers with high reproducibility and convenience in laboratories.

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“…We often try the MagOD system with suspension of magnetic micro-and nanoparticles. This works particularly well for magnetic needles [244] or magnetic discs [245]. In principle, spherical particles should not show a change in transmission under rotation of an external field.…”

Section: Suspensions Of Magnetic Nanoparticlesmentioning

confidence: 99%

Robot-assisted biopsies on mr-detected lesions

Welleweerd¹

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Quantifying and dispensing of magnetic particles in a self-assembled magnetic particle array

Cited by 4 publications

References 16 publications

An open-source automated magnetic optical density meter for analysis of suspensions of magnetic cells and particles

An open-source automated magnetic optical density meter for analysis of suspensions of magnetic cells and particles

All‐in‐one platform: Versatile, Easy, and User‐friendly System (VEUS) based on automated and expert‐independent antibody immobilization and immunoassay by utilizing customized movement of magnetic particles

Robot-assisted biopsies on mr-detected lesions

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