Quantitating Cataract and Nuclear Brunescence, The Harvard and LOCS Systems

Chylack, Leo T.; Wolfe, John K.; Friend, Judith; Khu, Patricia M.; Singer, David M.; McCarthy, Daniel F.; Carmen, Johanna del; Rosner, Bernard

doi:10.1097/00006324-199311000-00005

Cited by 31 publications

(18 citation statements)

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“…[24][25][26][27] New techniques such as photon spectroscopy for in vivo analysis of lenses remain to be further investigated. 28 Other workers have studied in vitro features such as size, 29 chemical, 30,31 dielectric properties 32 or histological appearance 33 of lenses and linked them with preoperative features such as nuclear colour, but have not examined nuclear hardness.…”

Section: Discussionmentioning

confidence: 99%

The relationship between nuclear colour and opalescence on the LOCSIII scale and physical characteristics of cataract nuclei

Smith

El-Brawany

Nassiri

et al. 2002

Eye

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Purpose To evaluate the compression characteristics of the human lens nucleocortex in relation to its LOCSIII clinical grading. Methods Sixteen subjects undergoing planned extracapsular cataract surgery had pre-operative slit-lamp examination and assessment of cataract LOCSIII grade followed by postoperative in vitro evaluation of the nucleus with measurement of 'linear compressibility' by a purpose-designed caliper incorporating a strain gauge, enabling the derivation of a graph of nuclear compression (D (mm) against applied force (F (N)). Results Nuclear colour correlates with the force required to compress a lens to 75% of its original depth (F75) (R = 0.625, P = 0.017). Nuclear opalescence correlates with the force required to compress a lens to 75% of its original depth (R = 0.651, P = 0.012) and inversely with linear compressibility (⌬D/⌬F, the slope of the graph of nuclear compression against applied force) (R = ؊0.610, P = 0.014). F75 is a direct and linear compressibility is an inverse related parameter of lens nucleus 'hardness'. Conclusion A new instrument is described which allows measurement of 'hardness'-related compression characteristics of the human cataract in vitro. There is a relationship between the LOCSIII clinical classification of nuclear cataracts and mechanical compression characteristics of the cataractous lens. LOCSIII classification may aid the preoperative planning of an appropriate surgical approach to an individual cataract.

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Section: Discussionmentioning

confidence: 99%

The relationship between nuclear colour and opalescence on the LOCSIII scale and physical characteristics of cataract nuclei

Smith

El-Brawany

Nassiri

et al. 2002

Eye

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“…3 This score system is based on slitlamp biomicroscopy and was validated in 1993. 4,5 Scheimpflug systems objectively measure lens density and might assist phacodynamics in cataract surgery. [6][7][8][9] Various methods for the measurement of lens optical densitometry have been used; however, there is still no consensus regarding this topic.…”

Section: J Cataract Refract Surg 2016; 42:405-411 Q 2016 Ascrs and Escrsmentioning

confidence: 99%

Scheimpflug lens densitometry and ocular wavefront aberrations in patients with mild nuclear cataract

Faria-Correia¹,

Lopes²,

Monteiro³

et al. 2016

Journal of Cataract and Refractive Surgery

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PURPOSE:To test correlations between Scheimpflug optical densitometry and ocular higher-order aberrations (HOAs) in patients with mild nuclear cataract.SETTING: Cornea and Refractive Surgery Department, Hospital de Braga, Braga, Portugal. DESIGN:Retrospective single-center study. METHODS:In eyes with mild nuclear cataract, lens densitometry was evaluated by Scheimpflug imaging (Pentacam HR), which provided an objective quantification (mean density and maximum density) and grading (nuclear staging score) of the crystalline lens. A visual function analyzer that combines ray-tracing aberrometry and Placido disk-based topography (iTrace) was used to evaluate the total ocular and internal HOAs. RESULTS:The study comprised 40 eyes of 30 patients. The mean density of the lens nucleus was 8.99% G 0.76% (SD) (range 7.5% to 10.8%), and the mean maximum density was 27.96% G 6.97% (range 16.9% to 56.1%). Regarding the score of nuclear staging of the Scheimpflug device, 28 eyes had level 0 and 12 eyes had level 1. Significant positive correlations were found between the mean density and maximum density parameters and the internal HOAs (r Z 0.661, P < .001 and r Z 0.570, P < .001, respectively).CONCLUSIONS: There were significant correlations between the quantification parameters derived from Scheimpflug lens densitometry and ocular HOAs. The integration of these technologies can help in clinical decision making and in understanding the subjective symptoms of patients with mild nuclear cataracts.

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“…The latter included examination of the anterior segment by a slit lamp and classification of lens opacity by the LOCS III system (Chylack et al, 1993). Only subjects with grade 2 or less for nuclear-, cortical-, and posterior subcapsular opacities were included in the study.…”

Section: Effect Of Normal Aging -Subject Selection Criteriamentioning

confidence: 99%