Quantitation of Atherosclerosis in Femoral Arteriography with Ecg Gated Exposures

Nilsson, Sven Erik G.; Berglund, I.; Bylund, Håkan; Erikson, Uno; Helmius, Gunnar; Hemmingsson, Anders; Holme, Ingar; Stenport, G; Walldius, Göran

doi:10.1177/028418518802900310

Cited by 12 publications

(8 citation statements)

References 13 publications

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“…Exposures were ECG gated with a delay of 100 ms from the R wave maximum. ECG gating was achieved by means of a triggering device described previously (2,17).…”

Section: Methodsmentioning

confidence: 99%

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Arterial segmental vasoconstriction in hypercholesterolaemic patients

Nilsson¹,

Berglund²,

Christoffersson³

et al. 1990

Acta Radiol

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“…Exposures were ECG gated with a delay of 100 ms from the R wave maximum. ECG gating was achieved by means of a triggering device described previously (2,17).…”

Section: Methodsmentioning

confidence: 99%

“…Roughness (in mm) is a measure of edge irregularity, defined as to correlate maximally with atherosclerotic wall involvement (20). Details of the digitizing procedure and the software routines of the image processing have been given elsewhere ( I , 17,18).…”

Section: Methodsmentioning

confidence: 99%

Arterial segmental vasoconstriction in hypercholesterolaemic patients

Nilsson¹,

Berglund²,

Christoffersson³

et al. 1990

Acta Radiol

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“…*Analysis using the modeling approach due to Rossner22 against a one-sided alternative. tCEA range: quartile 1 (11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)(24)(25)(26)(27), quartile 2 (28-35), quartile 3 (36-48), quartile 4 (49-180). groups (Figure 1).…”

Section: Per-patient Analysismentioning

confidence: 99%

Effects of colestipol-niacin therapy on human femoral atherosclerosis.

et al. 1991

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The 2-year therapy effect on femoral atherosclerosis was evaluated in the Cholesterol Lowering Atherosclerosis Study (CLAS), a randomized, placebo-plus-diet-controlled angiographic trial of colestipol-niacin therapy plus diet in men with previous coronary bypass surgery. Different diet compositions were prescribed to enhance the differential in blood cholesterol responses between the two groups. The annual rate of change in computer-estimated atherosclerosis (CEA), a measure of lumen abnormality, was evaluated between treatment groups. A significant per-segment therapy effect was found in segments with moderately severe atherosclerosis (p less than 0.04) and in proximal segments (p less than 0.02). When segmental CEA measures were combined into a per-patient score using an adaptation of the National Heart, Lung, and Blood Institute scoring procedure, a significant therapy effect was observed (p less than 0.02). Total variance of the annual change rate in CEA was as predicted from pilot studies, but measurement variation was larger. The therapy effect observed in femoral arteries, although significant, was less marked than the strong and consistent benefit previously reported for both native coronary arteries and aortocoronary bypass grafts.

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“…Thus the reproducibility is too low for application of the analysis in short longitudinal studies. However, ECG gated exposure during the angiography might increase the reproducibility (5).…”

Section: Visual Estimationmentioning

confidence: 99%

Repeat Femoral Arteriography in Hyperlipidemic Patients

Erikson¹,

Helmius²,

Hemmingsson³

et al. 1988

Acta Radiol

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Femoral arteriography was performed in 62 patients with significant hyperlipidemia. Sixty were asymptomatic and two had intermittent claudication. The patients participated in a study aiming to demonstrate whether serum lipid lowering by drugs could influence the development of femoral artery atheromatous disease. Half of the patients were treated with fenofibrate and nicotinic acid and the other half served as a control group. At the first arteriography atherosclerotic lesions were found in 46 of the 62 patients (74%). Arteriography was repeated up to three times without complications. Visual analysis of angiograms revealed considerable inter-observer variation. An attempt was made to assess the angiograms by a computerized method which, however, still needs improvement and a computer designed for image analysis. Most patients had small or moderate atheromatous deposits in the femoral artery at the initial examination, in most cases showing no change during the study period of 18 months. Regression was found in five patients of the treated group, but in none of the control patients as judged by visual gradation (p

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Quantitation of Atherosclerosis in Femoral Arteriography with Ecg Gated Exposures

Cited by 12 publications

References 13 publications

Arterial segmental vasoconstriction in hypercholesterolaemic patients

Arterial segmental vasoconstriction in hypercholesterolaemic patients

Effects of colestipol-niacin therapy on human femoral atherosclerosis.

Repeat Femoral Arteriography in Hyperlipidemic Patients

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