Quantitative analysis of polychlorinated biphenyls, organochlorine insecticides, polycyclic aromatic hydrocarbons, polychlorinated hydrocarbons and polynitrohydrocarbons in spiked samples of soil, water and plasma by selected-ion monitoring gas chromatography–mass spectrometry

Quantitative dynamics of PCB transfer from mother to pup during lactation in UK grey seals Halichoerus grypus

“…The sample preparation was set up by adapting a method established by the Laboratory of Food Analysis (University of Liège, Belgium) according to Singh et al (1998), Janak et al (1999, Pauwels et al (1999) and Frenich et al (2000). Serum was first deproteinised by adding 100 µl of triethylamine and 10 ml of formic acid to a precisely known volume of sample (from 2.5 to 10 ml, depending on the amount of sample available).…”

Rapid multiresidue determination of organochlorine and organophosphorus compounds in human serum by solid-phase extraction and gas chromatography coupled to tandem mass spectrometry

“…Determination of pesticides and PCBs in human body fluids is generally carried out by applying solvent extraction procedures [1,2,3,4,5,6] or by means of solidphase extraction (SPE) normally using C 18 cartridges [5,7,8,9,10] or C 18 disks [11,12,13]. Most of the analysis procedures reported for serum and blood require the application of cleanup steps to remove interferences (such as the presence of fat and the protein fraction of these complex matrices) and to improve detection limits.…”

Simple Isotope Dilution Headspace-GC-MS Analysis of Naphthalene and p-Dichlorobenzene in Whole Blood and Urine

“…However, the recovery rates are low, especially for lipophilic compounds present in various matrices containing large amounts of lipids and/or proteins, such as whole blood and tissue homogenates. 18,19 This is probably the reason why most of the previous studies [4][5][6][7][8][9][10][11][12] on the analysis of polycyclic aromatic hydrocarbons or volatile organic compounds including naphthalene and/or p-dichlorobenzene did not deal with whole blood samples. However, in postmortem forensic toxicological analysis, hemolyzed whole blood should be frequently analyzed.…”

“…There have been many reports on the analysis of polycyclic aromatic hydrocarbons or volatile organic compounds including naphthalene and/or p-dichlorobenzene in water, soil and plant samples, [4][5][6][7][8] in workers' urine, 9-11 and workers' plasma 5,12 by gas chromatography-mass spectrometry (GC-MS). However, most of the above reports have dealt with screening tests for many compounds from a viewpoint of environmented chemistry.…”