2007
DOI: 10.1016/j.jpba.2007.01.049
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Quantitative analysis of sulfur-related metabolites during cadmium stress response in yeast by capillary electrophoresis–mass spectrometry

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Cited by 37 publications
(13 citation statements)
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“…It is not clear whether the depletion of these metabolites is from the reduced biosynthesis or the enhanced catabolism. Recent study with yeast cells, treated with cadmium have shown that glycine level was rapidly decreased in cadmium-treated yeast while the concentrations of serine and homoserine were increased (Tanaka et al, 2007). Similar response has also been found in this study (Table 2).…”
Section: Resultssupporting
confidence: 91%
“…It is not clear whether the depletion of these metabolites is from the reduced biosynthesis or the enhanced catabolism. Recent study with yeast cells, treated with cadmium have shown that glycine level was rapidly decreased in cadmium-treated yeast while the concentrations of serine and homoserine were increased (Tanaka et al, 2007). Similar response has also been found in this study (Table 2).…”
Section: Resultssupporting
confidence: 91%
“…Há também vários trabalhos mostrando a eficiência do emprego de CE-MS em estudos metabólicos em fluidos biológicos de origem animal e vegetal. [94][95][96][97] Soga et al 98 descreveram um método para separação e detecção de 1.859 analitos em extratos de figado de rato e estudaram múltiplas mudanças em níveis metabólicos, incluindo a ativação da rota da biossíntese do oftalmato. Esse trabalho mostra que a CE-MS é uma poderosa ferramenta na descoberta de biomarcadores de baixa massa molecular, relacionados ao stress oxidativo.…”
Section: 87-90unclassified
“…For example, a Beckman and/or Agilent CE coupled with a Thermo Finnigan and/or Bruker MS through an ESI interface [11][12][13] are both operated by two different software programs. 2-D separation can be an interesting and useful separation technique that effectively reveals important data.…”
Section: Cementioning
confidence: 99%
“…Deelder and co-workers [124] used CE-TOF MS to analyze nanomolar detection of several metabolites such as amino acids, amines, and small peptides, from the body fluids of patients suffering from osteoarthritis. Soga and co-workers [10] developed a new approach of metabolic flux analysis using isotope labeling of 13 C. In this investigation, they used CE-TOF MS to detect and measure the intracellular metabolites of E. coli. Since this work discussed flux balance analysis (FBA), it was seen as helpful to systems biology researchers.…”
Section: Ce In Metabolomicsmentioning
confidence: 99%