Quantitative analysis of TEGDMA and HEMA eluted into saliva from two dental composites by use of GC/MS and tailor-made internal standards

Michelsen, Vibeke Barman; Moe, Grete; Strøm, Morten B.; Jensen, Einar; Lygre, Henning

doi:10.1016/j.dental.2007.08.002

Cited by 66 publications

(55 citation statements)

References 25 publications

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“…If these materials have toxic characteristics, then they may cause inflammatory reactions in periapical tissues [1,2] and can interact with biomolecules in tissues. This interaction can damage living tissues [3][4][5][6]. Recently, the materials with toxic characteristics have been determined by using various methods [7][8][9][10].…”

Section: Introductionmentioning

confidence: 99%

In Vitro Analysis of AHPlus and MM-Seal by ESR and Thermoanalytical Methods

Ceylan

Usta

et al. 2015

Acta Phys. Pol. A

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The free radicals and their concentration in resin materials may impact biocompatibility and polymerization properties of dental materials. The aim of this study was to determine whether there are free radicals and to obtain useful information about thermal stability of materials using electron spin resonance (ESR) spectroscopy, TGA (Thermogravimetry Analysis) and DTA (Differential Thermal Analysis) methods. Epoxy resin-based sealers AHPlus and MM-Seal samples, freshly mixed and set, were prepared to be analysed with ESR and thermal methods. The free radicals were found in dental materials. As radical concentration in AHPlus have changed very slowly, the concentration in MM-Seal have decreased dramatically. Also, MM-Seal was found to decompose in three steps with the increasing temperature, while decomposition of the AHPlus occurred in two steps.

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Section: Introductionmentioning

confidence: 99%

In Vitro Analysis of AHPlus and MM-Seal by ESR and Thermoanalytical Methods

Ceylan

Usta

et al. 2015

Acta Phys. Pol. A

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“…This leads to the accumulation of monomers within the composite resins and subsequent cytotoxic effects. Previous studies have demonstrated that composite resins release tri-ethylene glycol di-meth-acrylate (TEGDMA) (13) in large quantities, and this may result in cellular damage in the pulp after diffusion through the dentin (14) The amount and growth rates of cultured cells exposed to test materials in in vitro cytotoxicity tests have been previously evaluated, and the test materials were considered to be non-cytotoxic if the cells stuck to the culture plate and continued to proliferate over time (15). Human dental pulp stem cells (hDPSC) have several advantages, such as easy procurement, minimum ethical problems, high potential of differentiation, ability to restructure tissues when utilized with biomaterials, long-term viability, and safe storage under freezing conditions (16,17).…”

Section: Introductionmentioning

confidence: 99%

Cytotoxic effects of bulk fill composite resins on human dental pulp stem cells

et al. 2016

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“…The manufacturer claims that these materials do not contain TEGDMA and HEMA, but there are some conflicting results published in the independent studies [8,13]. These monomers are considered to be one of the most cyto-and genotoxic in dental resinbased materials [19,28].…”

Section: Discussionmentioning

confidence: 93%

“…Ethanol is most commonly used, but the results indicate that saliva might be more appropriate because of the low Bis-GMA values obtained from composites immersed in ethanol [11]. The amount of released substances can be detected by using high-performance liquid chromatography [8], liquid chromatographymass spectrometry [6,12] and gas chromatographymass spectrometry [13].…”

Section: Introductionmentioning

confidence: 99%