2019
DOI: 10.1002/mp.13503
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Quantitative assessment of breast density using transmission ultrasound tomography

Abstract: Purpose Breast density is important in the evaluation of breast cancer risk. At present, breast density is evaluated using two‐dimensional projections from mammography with or without tomosynthesis using either (a) subjective assessment or (b) a computer‐aided approach. The purpose of this work is twofold: (a) to establish an algorithm for quantitative assessment of breast density using quantitative three‐dimensional transmission ultrasound imaging; and (b) to determine how these quantitative asse… Show more

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Cited by 39 publications
(35 citation statements)
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“…This research was funded in part by the Swiss National Science Foundation (project number 205320 178038) and the European Union's Horizon 2020 research and innovation programme under grant agreement No 732411, Photonics Private Public Partnership, and is supported by the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number 16.0162. The opinions expressed and arguments employed herein do not necessarily reflect the official view of the Swiss Government.…”
Section: Introductionmentioning
confidence: 99%
“…This research was funded in part by the Swiss National Science Foundation (project number 205320 178038) and the European Union's Horizon 2020 research and innovation programme under grant agreement No 732411, Photonics Private Public Partnership, and is supported by the Swiss State Secretariat for Education, Research and Innovation (SERI) under contract number 16.0162. The opinions expressed and arguments employed herein do not necessarily reflect the official view of the Swiss Government.…”
Section: Introductionmentioning
confidence: 99%
“…That algorithm maintains the projection-like geometry of Radon and diffraction tomography but includes nonlinear and extended refraction and diffraction effects. This algorithm, first proved in the context of the breast [51][52][53] , is extended to include bone by the careful choice of alternative frequencies and iteration counts at each frequency. This extension of the algorithm to these more difficult cases involving bone, is analogous to the use of different 'sequences' in MR imaging.…”
Section: Resultsmentioning
confidence: 99%
“…We observed an average of 9.4% with a standard deviation of 0.2%. Since the ratio is based upon quantitative speed of sound 52 this indicates the stability of the transmission ultrasound reconstructions.…”
Section: Resultsmentioning
confidence: 99%
“…1,2 Although mammography is widely used for early detection of breast cancer, it shows low detection performance for women with dense breasts. 3 Moreover, it is an ionizing radiation examination and a history of mammography may increase the risk of breast cancer. 4 Hand-held ultrasound (HHUS) is an important imaging technique in complementary to breast mammography.…”
Section: Introductionmentioning
confidence: 99%
“…Breast cancer is one of the leading causes of cancer death in women and early detection is essential to reduce mortality and improve prognosis 1,2 . Although mammography is widely used for early detection of breast cancer, it shows low detection performance for women with dense breasts 3 . Moreover, it is an ionizing radiation examination and a history of mammography may increase the risk of breast cancer 4 .…”
Section: Introductionmentioning
confidence: 99%