Quantitative assessment of moniliformin in cereals via alternative precipitation pathways, aided by LC-LIT-MS and LC-Q-TOF-MS

Stability of Mycotoxins in Individual Stock and Multi-Analyte Standard Solutions

“…Filek et al reported water solution of MO (1 mg/mL) to be stable for at least three months when refrigerated [79]. Furthermore, 1-75 ng/mL MO calibrants dissolved in aqueous 0.1% acetic acid underwent about 50% degradation within two weeks storage at 4 • C and the authors recommended practicing the fresh preparation of MO calibrants as a quality control strategy [80]. CIT (0.5-100 µg/mL) methanol standard solutions were stable at room temperature for 24 h [81].…”

Cytochrome P450-derived epoxyeicosatrienoic acids and coronary artery disease in humans: a targeted metabolomics study

“…Dried extracts were reconstituted in 80% methanol (containing 10 mg/ml BHT) for elution through phospholipid removal columns (Phree; Phenomenex, Torrance, CA), as directed by the manufacturer. Phospholipid removal enhances purifi cation of the extracts, thereby reducing matrix ion suppression and improving signal-to-noise ratio ( 16 ). Phospholipid-free extracts were then dried a second time by centrifugation under vacuum and stored at Ϫ 80°C.…”

Advanced Mass Spectrometry

“…This has made TOF-MS an essential instrument for food analysis applications-typically with matrix-assisted laser desorption/ionization (MALDI) and ESI ionization-particularly with the development of high-resolution and hybrid instruments [quadrupole time-offlight (QqTOF), ion-trap time-of-flight (IT-TOF), and TOF-TOF configurations]. These hybrid instruments benefit from the versatile ability of quadrupoles to carry out various tasks and from the high performance of TOF spectrometers in both MS and MS/MS modes [42][43][44][45][46][47]. The QqTOF is a hybrid quadrupole TOF mass spectrometer with MS/MS capability.…”

“…Effect of thermal processing [66] LC-TOF Analysis of pesticides in fruits and vegetables [67] GC-TOF Quantitative analysis of acetaldehyde in foods consumed [68] LC-TOF Screening natural antioxidants in peanut shell [69] UHPLC-TOF Hexabromocyclododecane diastereomers [70] Type Application References UHPLC-TOF 19 antibiotics in dairy products [71] MALDI-TOF Microscale strategy to detect spermine and spermidine in food [72] LC-TOF Determination of phthalates in edible salts from food markets in Korea [73] LC-QqTOF Simultaneous determination five major antioxidant compounds [74] MALDI-TOF Monitoring of she-donkey's milk contamination or adulteration [75] MALDI-TOF Quantitating curcumin in food condiments and dietary supplements and screening of acrylamide-induced ROS protein indicators [76] LC-QqTOF Quantitating curcumin in food condiments and dietary supplements and screening of acrylamide-induced ROS protein indicators [45] UHPLC-TOF Analysis of illicit dietary supplements sold in the Italian market: Identification of a sildenafil thioderivative as adulterant [46] LC-TOF Simultaneous investigation of sesquiterpenes, pyrrolizidine alkaloids, and N-oxides in butterbur (Petasites hybridus) [77] UHPLC-QqTOF Determination of 141 pesticides in tea [78] UHPLC-QqTOF Determination of tadalafil and N-desmethylsibutramine in health and dietary supplements [79] LC-QqTOF Seven fluorescent whitening agents in food contact paper package materials [80] Lipidomics GC × GC-TOF Unsaponifiable fraction of lipids belonging to various types of milk [22] UHPLC-QqTOF Rapid and highly accurate detection of steryl glycoside [81] MALDI-TOF Rapid lipid profiling of bacteria [82] MALDI-TOF Detection of glycated phospholipids in heattreated food samples [83] …”

“…The use of LC-TOF-HRMS methods can also be found in a variety of analytical applications [45,46]. Their major disadvantage in comparison to MALDI is the time required for the chromatographic separation.…”