2009
DOI: 10.1016/j.jri.2009.02.007
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Quantitative comparison of stem cell marker-positive cells in fetal and term human amnion

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Cited by 56 publications
(45 citation statements)
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“…However, few studies to date have clarified whether the gestational stage of isolation may affect the differentiation potential of AECs [31, 44]. The results obtained in the present study show that sheep AECs greatly changed their phenotype, stemness properties, as well as, their in vitro plasticity during gestation, while they maintained unaltered the immunomodulatory activities.…”
Section: Discussionmentioning
confidence: 50%
See 1 more Smart Citation
“…However, few studies to date have clarified whether the gestational stage of isolation may affect the differentiation potential of AECs [31, 44]. The results obtained in the present study show that sheep AECs greatly changed their phenotype, stemness properties, as well as, their in vitro plasticity during gestation, while they maintained unaltered the immunomodulatory activities.…”
Section: Discussionmentioning
confidence: 50%
“…In fact, Nakajima et al [30] demonstrated a reduction of telomerase activity in rat AECs collected at the end of gestation, while Izumi et al [31] showed that there is a reduced expression in stem cell markers in human term amnion compared to fetal ones.…”
Section: Introductionmentioning
confidence: 99%
“…To determine whether HCMV infects AmEpCs, primary cells isolated from mid-gestation and late gestation placentas were infected with VR1814. Immunostaining of control AmEpCs, which have the properties of fetal stem cells, 22,29,44 revealed expression of the pluripotency proteins Oct4 and SOX2, the embryonic stem celle specific surface antigen stage-specific embryonic antigen-4, 45 and the transcription factors GATA-3 and Hand-1, regulators of cell differentiation 44 ( Figure 2A). Late in infection, when gB and pp28 were expressed, Oct4, SOX2, stage-specific embryonic antigen-4, GATA3, and Hand1 were down-regulated (Figure 2A).…”
Section: Persistent Hcmv Infection In Primary Amepcs In Vitromentioning
confidence: 99%
“…More recently, comparative analysis of hAEC from amnion of early-stage pregnancies and from term amnion showed that expression of the stem cell-specifi c cell surface markers TRA1-60 and TRA1-81, and of the molecular markers of pluripotency Nanog and Sox2, are all signifi cantly higher in fetal amnion, while expression of Oct-4 mRNA is similar between cells obtained either from fetal or term amnion [ 20 ].…”
Section: Mechanisms Of Infl Ammatory Disease: Will An Increased Undermentioning
confidence: 99%