Quantitative description and local structures of trivalent metal ions Eu(III) and Cm(III) complexed with polyacrylic acid

Montavon, Gilles; Bouby, M.; Huclier‐Markai, Sandrine; Grambow, Bernd; Geckeis, Horst; Rabung, Thomas; Pashalidis, Ioannis; Amekraz, Badia; Moulin, Christophe

doi:10.1016/j.jcis.2008.08.037

Cited by 9 publications

(8 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…biological systems) are urgently needed. In the last few years the popularity of on-line field-flow fractionation (FFF) coupled with inductively coupled plasma mass spectrometry (ICP-MS) in the characterisation of various nanomaterials has increased significantly [1][2][3][4][5][6][7][8]. FFF-ICP-MS allows NP sizing, size-based elemental speciation and quantification of the nano-sized fraction in the presence of complex matrix components.…”

Section: Introductionmentioning

confidence: 99%

Total synthesis of isotopically enriched Si-29 silica NPs as potential spikes for isotope dilution quantification of natural silica NPs

Pálmai

Szalay

Bartczak³

et al. 2015

Journal of Colloid and Interface Science

View full text Add to dashboard Cite

A new method was developed for the preparation of highly monodisperse isotopically enriched Si-29 silica nanoparticles ( 29 Si-silica NPs) with the purpose of using them as spikes for isotope dilution mass spectrometry (IDMS) quantification of silica NPs with natural isotopic distribution. Si-29 tetraethyl orthosilicate ( 29 Si-TEOS), the silica precursor was prepared in two steps starting from elementary silicon-29 pellets. In the first step Si-29 silicon tetrachloride ( 29 SiCl 4 ) was prepared by heating elementary silicon-29 in chlorine gas stream. By using a multistep cooling system and the dilution of the volatile and moisturesensitive 29 SiCl 4 in carbon tetrachloride as inert medium we managed to reduce product loss caused by evaporation. 29 Si-TEOS was obtained by treating 29 SiCl 4 with absolute ethanol.Structural characterisation of 29 Si-TEOS was performed by using 1 H and 13 C nuclear magnetic resonance (NMR) spectroscopy and Fourier-transform infrared (FTIR) spectroscopy. For the NP preparation, a basic amino acid catalysis route was used and the resulting NPs were analysed using transmission electron microscopy (TEM), small angle Xray scattering (SAXS), dynamic light scattering (DLS) and zeta potential measurements.

show abstract

Section: Introductionmentioning

confidence: 99%

Total synthesis of isotopically enriched Si-29 silica NPs as potential spikes for isotope dilution quantification of natural silica NPs

Pálmai

Szalay

Bartczak³

et al. 2015

Journal of Colloid and Interface Science

View full text Add to dashboard Cite

show abstract

“…PS‐ b ‐PAA forms spherical core–shell micelles in solution; the core is composed of the PS block and the shell is composed of the PAA block (Scheme ), which is partially proven by dynamic light scattering (Supporting Information, Figure S6) 15. The PAA shell integrates the RE salts by forming coordination bonds and electrostatic interactions with the RE ions, as indicated by the increase in size of the micelles in solution from the DLS result (Supporting Information, Figure S6) and the powder FTIR spectrum (Supporting Information, Figure S7) 16. Sol–gel reaction of the RE salts proceeds within the PAA shell to form the oxide network.…”

Section: Resultsmentioning

confidence: 91%

Generalized Synthesis of Mesoporous Rare Earth Oxide Thin Films through Amphiphilic Ionic Block Copolymer Templating

et al. 2013

View full text Add to dashboard Cite

A new concept to achieve the generalized synthesis of crystalline mesoporous rare earth (RE) oxide thin films templated with an ionic amphiphilic block copolymer is developed. thin films as representatives of the light and heavy RE groups are synthesized by using polystyrene-block-poly(acrylic acid) (PS-b-PAA) as a templating agent. The impact of the concentration of PS-b-PAA on the morphologies of the mesopores is investi-

show abstract

“…Both spectroscopic observations are coherent with studies conducted in similar conditions with polyelectrolyte-containing carboxylic groups. 26 The complex between Cm(III) and the functional groups of the BGG is not thermodynamically stable since its contribution becomes negligible (<3%) at equilibrium, i.e. for a contact time above 300 min (data not shown).…”

Section: Coordination Properties Of Bgg-bound and Free Chx-a′′-dtpamentioning

confidence: 98%

“…Peak position and shape of the fluorescence emission spectra associated with the 6 D′ 7/2 → 8 S′ 7/2 transition of Cm(III) are sensitive to the first coordination sphere around Cm(III) 25 and for a given coordination sphere, to the spatial organization. 26 In a similar manner, the fluorescence lifetime provides information about the number of water molecules in the coordination sphere and then the number of coordination sites occupied by the ligand considering a total coordination number of 9 around Cm(III). 27 Cm(III) complexation by CHX-A′′-DTPA-BGG conjugate was studied by TRLFS as a function of the time (Fig.…”

Section: Coordination Properties Of Bgg-bound and Free Chx-a′′-dtpamentioning

confidence: 99%

DTPA complexation of bismuth in human blood serum

Montavon

Champion

et al. 2012

Dalton Trans.

Self Cite

View full text Add to dashboard Cite

The in vivo(212)Pb/(212)Bi generator is promising for application in targeted alpha therapy (TAT) of cancer. One main limitation of its therapeutic application is due to potential release of (212)Bi from the radioconjugate upon radioactive decay of the mother nuclide (212)Pb, potentially leading to irradiation of healthy tissue. The objective of the present work is to assess whether the chelate CHX-A''-DTPA (N-(2-aminoethyl)-trans-1,2-diaminocyclohexane-N,N',N''-pentaacetic acid) bound to a biological carrier molecule may be able to re-complex released (212)Bi under in vivo conditions to limit its translocation from the target site. CHX-A''-DTPA was bound to bovine gamma globulin (BGG) to mimic a model conjugate and the stability of the Bi-CHX-A''-DTPA-BGG conjugate was studied in blood serum by ultrafiltration. TRLFS experiments using Cm(III) as a fluorescent probe demonstrated that linking CHX-A''-DTPA to BGG does not affect the coordination properties of the ligand. Furthermore, comparable stability constants were observed between Bi(III) and free CHX-A''-DTPA, BGG-bound CHX-A''-DTPA and DTPA. The complexation constants determined between Bi(III) and the chelate molecules are sufficiently high to allow ultra trace amounts of the ligand to efficiently compete with serum transferrin controlling Bi(III) speciation in blood plasma conditions. Nevertheless, CHX-A''-DTPA is not able to complex Bi(III) generated in blood serum because of the strong competition between Bi(III) and Fe(II) for the ligand. In other words, CHX-A''-DTPA is not "selective" enough to limit Bi(iii) release in the body when applying the (212)Pb/(212)Bi in vivo generator.

show abstract

Quantitative description and local structures of trivalent metal ions Eu(III) and Cm(III) complexed with polyacrylic acid

Cited by 9 publications

References 20 publications

Total synthesis of isotopically enriched Si-29 silica NPs as potential spikes for isotope dilution quantification of natural silica NPs

Total synthesis of isotopically enriched Si-29 silica NPs as potential spikes for isotope dilution quantification of natural silica NPs

Generalized Synthesis of Mesoporous Rare Earth Oxide Thin Films through Amphiphilic Ionic Block Copolymer Templating

DTPA complexation of bismuth in human blood serum

Contact Info

Product

Resources

About